FAQ

Complement Receptor Type 2

Known as: EBV Receptor, Epstein-Barr Virus Receptor, CD21 Antigen 
Complement receptor type 2 (1033 aa, ~113 kDa) is encoded by the human CR2 gene. This protein plays a role in the activation of complement-mediated… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1948-2017
020406019482016

Related topics

Related topics

9 relations
B Cell Receptor Signaling PathwayComplement ActivationComplement System ProteinsImmunity
(More)

Broader (2)

CR2 geneCR2 wt Allele

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Complement Receptor Type 2
Plasma membrane
Immunity
Complement System Proteins
Complement Activation
Receptors, Cell Surface

Papers overview

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Highly Cited
2002
Highly Cited
2002
Mice deficient in complement receptors 1 and 2 lack a tissue injury-inducing subset of the natural antibody repertoire.
Intestinal ischemia-reperfusion (IR) injury is initiated when natural Abs recognize neoantigens that are revealed on ischemic… (More)
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Highly Cited
2002
Highly Cited
2002
Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus.
OBJECTIVE To investigate the fate of apoptotic cells in the germinal centers (GCs) of patients with systemic lupus erythematosus… (More)
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Highly Cited
1997
Highly Cited
1997
Mouse complement receptors type 1 (CR1;CD35) and type 2 (CR2;CD21): expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice.
Human complement receptors type 1 (hCR1;CD35) and type 2 (hCR2;CD21) are expressed on B lymphocytes at specific stages during… (More)
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Highly Cited
1996
Highly Cited
1996
Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2.
Complement receptor 1 (CR1, CD35) and complement receptor 2 (CR2, CD21) have been implicated as regulators of B-cell activation… (More)
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Highly Cited
1996
Highly Cited
1996
Antibody response to a T-dependent antigen requires B cell expression of complement receptors
Several lines of evidence indicate that antibody responses to T-dependent antigens require complement receptors expressed on… (More)
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Highly Cited
1991
Highly Cited
1991
Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19
The complement system augments the humoral immune response, possibly by a mechanism that involves the B lymphocyte membrane… (More)
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Highly Cited
1990
Highly Cited
1990
In vivo inhibition of the antibody response by a complement receptor- specific monoclonal antibody
BALB/c mice were injected intravenously with three different monoclonal antibodies (mAbs) specific for complement receptor 1 (CR1… (More)
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1989
1989
Identification of murine complement receptor type 2.
A rabbit antiserum reactive with the human complement component C3d/Epstein-Barr virus receptor (complement receptor type 2, CR2… (More)
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Highly Cited
1988
Highly Cited
1988
Synergistic interaction between complement receptor type 2 and membrane IgM on B lymphocytes.
We sought biochemical evidence for a role of C receptors types 1 (CR1) and 2 (CR2) in B cell activation. A flow cytometer was… (More)
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Highly Cited
1984
Highly Cited
1984
Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.
Identity of the Epstein-Barr virus (EBV) receptor with the complement receptor type 2 (CR2) was established in three sets of… (More)
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