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Complement Factor I
Known as:
Inactivator, Complement C4b-C3b
, C4b-C3b Inactivator, Complement
, Complement 3b Complement 4b Inactivator
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A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein…
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National Institutes of Health
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Related topics
Related topics
12 relations
CFI gene
Complement C3 Convertases
Fibrinogen
Process of secretion
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Broader (2)
Complement 3b Inactivators
Complement Inactivating Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Immune lysis of Trypanosoma congolense: generation of a soluble covalent complex of variant surface glycoprotein and bovine complement component C3b.
E. Liu
,
E. Otesile
,
H. Tabel
Veterinary Immunology and Immunopathology
1993
Corpus ID: 22944383
Highly Cited
1985
Highly Cited
1985
Binding of complement component C3b to glycoprotein C is modulated by sialic acid on herpes simplex virus type 1-infected cells
M. Smiley
,
H. Friedman
Journal of Virology
1985
Corpus ID: 40686761
Neuraminidase treatment of cells infected with herpes simplex virus type 1 (HSV-1) markedly enhanced the binding of complement…
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Highly Cited
1985
Highly Cited
1985
Sequential studies of complement activation in systemic lupus erythematosus.
G. Sturfelt
,
U. Johnson
,
A. Sjöholm
Scandinavian Journal of Rheumatology
1985
Corpus ID: 1325185
C1 and C3 activation, measured as C1r-C1s-C1 inactivator C1s-C1r-C1IA complexes in serum and circulating C3d were studied in…
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1982
1982
C3b inactivator deficiency with immune complex manifestations.
P. Solal-Céligny
,
M. Laviolette
,
+5 authors
J. Delâge
Clinical and Experimental Immunology
1982
Corpus ID: 8009015
We report a complete C3b inactivator deficiency in a 28-year-old patient referred for bronchiectasis and recurrent pneumonia. In…
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1981
1981
The separation of functionally distinct forms of the third component of human complement (C3).
Catherine Parkes
,
R. Discipio
,
Michael A. KERRt
,
Rainer PROHASKAt
Biochemical Journal
1981
Corpus ID: 22183929
Complement component C3 prepared by the method of Tack & Prahl [(1976) Biochemistry 15, 4513-4521] was found to contain the…
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1980
1980
Control of serum C3 levels by beta 1H and C3b inactivator.
R. Wyatt
,
J. Forristal
,
C. A. Davis
,
T. Coleman
,
C. West
Journal of Laboratory and Clinical Medicine
1980
Corpus ID: 559855
In serum specimens from 50 normal adults, a high correlation was found between the sum of the levels of the control proteins of…
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1977
1977
Correlations between serum factor B and C3b inactivator levels in normal subjects and in patients with infections, nephrosis and hypocomplementaemic glomerulonephritis.
J. Forristal
,
K. Iitaka
,
E. Vallota
,
C. West
Clinical and Experimental Immunology
1977
Corpus ID: 19164512
In normal subjects, factor B and C3b inactivator (KAF) levels were linearly related (r = 0-71); factor B levels in subjects with…
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1976
1976
Studies of the presence of membrane receptors for complement, IgG and the sheep erythrocyte rosetting capacity on the same human lymphocytes
J. Chiao
,
R. A. Good
European Journal of Immunology
1976
Corpus ID: 37088535
Normal peripheral blood lymphocytes were tested by a mixed rosette method, employing different sized erythrocytes as indicators…
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Highly Cited
1975
Highly Cited
1975
Isolation and analysis of the mechanism of action of an inactivator of C4b in normal human serum
N. Cooper
Journal of Experimental Medicine
1975
Corpus ID: 14947766
A complement regulatory principle, C4b inactivator, was isolated in a partially purified form from normal human serum. The C4b…
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Highly Cited
1974
Highly Cited
1974
RECEPTOR FOR SOLUBLE C3 AND C3b ON HUMAN LYMPHOBLASTOID (RAJI) CELLS
A. Theofilopoulos
,
V. Bokisch
,
F. Dixon
Journal of Experimental Medicine
1974
Corpus ID: 11066133
This study describes the presence of a receptor for fluid phase human C3 and C3b on Raji cell membranes. The binding of C3 and…
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