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Complement Factor I

Known as: Inactivator, Complement C4b-C3b, C4b-C3b Inactivator, Complement, Complement 3b Complement 4b Inactivator 
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein… 
National Institutes of Health

Papers overview

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Highly Cited
1985
Highly Cited
1985
Neuraminidase treatment of cells infected with herpes simplex virus type 1 (HSV-1) markedly enhanced the binding of complement… 
Highly Cited
1985
Highly Cited
1985
C1 and C3 activation, measured as C1r-C1s-C1 inactivator C1s-C1r-C1IA complexes in serum and circulating C3d were studied in… 
1982
1982
We report a complete C3b inactivator deficiency in a 28-year-old patient referred for bronchiectasis and recurrent pneumonia. In… 
1981
1981
Complement component C3 prepared by the method of Tack & Prahl [(1976) Biochemistry 15, 4513-4521] was found to contain the… 
1980
1980
In serum specimens from 50 normal adults, a high correlation was found between the sum of the levels of the control proteins of… 
1977
1977
In normal subjects, factor B and C3b inactivator (KAF) levels were linearly related (r = 0-71); factor B levels in subjects with… 
1976
1976
Normal peripheral blood lymphocytes were tested by a mixed rosette method, employing different sized erythrocytes as indicators… 
Highly Cited
1975
Highly Cited
1975
A complement regulatory principle, C4b inactivator, was isolated in a partially purified form from normal human serum. The C4b… 
Highly Cited
1974
Highly Cited
1974
This study describes the presence of a receptor for fluid phase human C3 and C3b on Raji cell membranes. The binding of C3 and…