Complement Factor I

Known as: Inactivator, Complement C4b-C3b, C4b-C3b Inactivator, Complement, Complement 3b Complement 4b Inactivator 
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein… (More)
National Institutes of Health

Papers overview

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2005
2005
New proteomics methods are required for targeting and identification of subsets of a proteome in an activity-based fashion. Here… (More)
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1985
1985
Neuraminidase treatment of cells infected with herpes simplex virus type 1 (HSV-1) markedly enhanced the binding of complement… (More)
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Highly Cited
1980
Highly Cited
1980
Short-term cultures of human peripheral blood monocytes were shown to synthesize the alternative pathway complement components C3… (More)
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Highly Cited
1979
Highly Cited
1979
We recently described the isolation from human serum of a serum protein (C4 binding protein) that functions as an essential… (More)
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Highly Cited
1978
Highly Cited
1978
The alternative or properdin pathway of complement is primarily controlled by the endopeptidase C3b inactivator (C3bINA) and the… (More)
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Highly Cited
1977
Highly Cited
1977
The complement regulatory enzyme, C3b inactivator (C3bINA), has been purified from human serum by affinity chromatography on an… (More)
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Highly Cited
1977
Highly Cited
1977
The surface of zymosan (Zy), by affording a protected microenvironment for C3b and the amplification convertase stabilized by… (More)
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Highly Cited
1976
Highly Cited
1976
An inhibitory activity for an erythrocyte in termediate bearing the properdin (P)-stabilized amplification C3 convertase, PC3bBb… (More)
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Highly Cited
1976
Highly Cited
1976
C3b inactivator accelerator (A-C3bINA) was isolated from human plasma. An antiserum produced against the purified protein gave a… (More)
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