Combinatorial Synthesis

Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2018
020406019782018

Papers overview

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2013
2013
Taking a nanoparticle (NP) from discovery to clinical translation has been slow compared to small molecules, in part by the lack… (More)
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2012
2012
This paper presents a droplet-based microfluidic platform for miniaturized combinatorial synthesis. As a proof of concept, a… (More)
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2009
2009
Protein tyrosine phosphatases (PTPs) regulate a broad range of cellular processes including proliferation, differentiation… (More)
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2007
2007
In this paper we describe the preparation of a hexapeptide library by combinatorial synthesis and the identification of a peptide… (More)
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2006
2006
To investigate one possible mechanism of action of the cytotoxic activity of benzothiazoles, we synthesized 2-(substituted-phenyl… (More)
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2004
2004
A method for accelerating the discovery of ionic luminophores using combinatorial techniques is reported. The photophysical… (More)
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1999
1999
BACKGROUND The development of estrogen pharmaceutical agents with appropriate tissue-selectivity profiles has not yet benefited… (More)
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1996
1996
BACKGROUND Protein-structure-based combinatorial chemistry has recently been used to discover several ligands containing non… (More)
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1995
1995
A concept termed liquid-phase combinatorial synthesis (LPCS) is described. The central feature of this methodology is that it… (More)
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1994
1994
A library of 192 structurally diverse 1,4-benzodiazepine derivatives containing a variety of chemical functionalities including… (More)
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