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Combinatorial Synthesis

Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made… 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
A new type of neutral donor–acceptor [2]-catenane, containing both complementary units in the same ring was synthesized from a… 
Highly Cited
2008
Highly Cited
2008
A convenient method of synthesis of substituted and annulated 2-amino-spiro[(3' H)-indol-3',4-(4 H)-pyrans] at mild conditions… 
Review
2008
Review
2008
For discovery of a new type of antiatherosclerotic agents, a cell-based assay of lipid droplet accumulation using primary mouse… 
Review
2006
Review
2006
Solid-phase organic synthesis (SPOS) has become an effective synthetic tool for the preparation of combinatorial libraries of non… 
Review
2004
Review
2004
Head-to-tail cyclic peptides have been reported to bind to multiple, unrelated classesof receptor with high affinity. They may… 
Review
2003
Review
2003
Lead identification and optimization is always a challenge to the medicinal chemists in drug discovery. Numbers of simple to… 
Highly Cited
2002
Highly Cited
2002
An efficient, facile, and practical liquid-phase combinatorial synthesis of benzimidazoles under microwave irradiation is… 
2001
2001
Abstract In the age of high-throughput screening and combinatorial chemistry, the focus of drug discovery is to replace the… 
2000
2000
A modular system for high-output solid-phase combinatorial synthesis has been designed and developed. The system employs three… 
1998
1998
A "basket in a basket" method based on a multistage accurate mass spectrometric (MAMS) technique was developed and demonstrated…