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Combinatorial Synthesis
Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made…
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National Institutes of Health
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Highly Cited
2009
Highly Cited
2009
Dynamic combinatorial synthesis of a catenane based on donor–acceptor interactions in water
H. Au-Yeung
,
G. Pantoș
,
J. Sanders
Proceedings of the National Academy of Sciences…
2009
Corpus ID: 332493
A new type of neutral donor–acceptor [2]-catenane, containing both complementary units in the same ring was synthesized from a…
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Highly Cited
2008
Highly Cited
2008
Versatile three-component procedure for combinatorial synthesis of 2-aminospiro[(3'H)-indol-3',4-(4H)-pyrans].
Y. Litvinov
,
V. Y. Mortikov
,
A. M. Shestopalov
Journal of combinatorial chemistry
2008
Corpus ID: 206873161
A convenient method of synthesis of substituted and annulated 2-amino-spiro[(3' H)-indol-3',4-(4 H)-pyrans] at mild conditions…
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Review
2008
Review
2008
Discovery and combinatorial synthesis of fungal metabolites beauveriolides, novel antiatherosclerotic agents.
H. Tomoda
,
T. Doi
Accounts of Chemical Research
2008
Corpus ID: 6534615
For discovery of a new type of antiatherosclerotic agents, a cell-based assay of lipid droplet accumulation using primary mouse…
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Review
2006
Review
2006
The polymer-supported and combinatorial synthesis of beta-lactam compounds: an update.
M. Laborde
,
E. G. Mata
Mini-Reviews in Medical Chemistry
2006
Corpus ID: 7701250
Solid-phase organic synthesis (SPOS) has become an effective synthetic tool for the preparation of combinatorial libraries of non…
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Review
2004
Review
2004
Exploring privileged structures: The combinatorial synthesis of cyclic peptides
Douglas A. Horton
,
G. Bourne
,
M. Smythe
Molecular diversity
2004
Corpus ID: 40460320
Head-to-tail cyclic peptides have been reported to bind to multiple, unrelated classesof receptor with high affinity. They may…
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Review
2003
Review
2003
Microwave-assisted polymer-supported combinatorial synthesis.
K. Swamy
,
Wen-Ben Yeh
,
Mei-Jung Lin
,
Chung‐Ming Sun
Current Medicinal Chemistry
2003
Corpus ID: 36987818
Lead identification and optimization is always a challenge to the medicinal chemists in drug discovery. Numbers of simple to…
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Highly Cited
2002
Highly Cited
2002
Rapid microwave-assisted liquid-phase combinatorial synthesis of 2-(arylamino)benzimidazoles.
Pravin M. Bendale
,
Chung‐Ming Sun
Journal of combinatorial chemistry
2002
Corpus ID: 21090906
An efficient, facile, and practical liquid-phase combinatorial synthesis of benzimidazoles under microwave irradiation is…
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2001
2001
Combinatorial chemistry. Facing the challenge of chemical genomics
F. Darvas
,
G. Dormán
,
L. Urge
,
I. Szabo
,
Z. Rónai
,
M. Sasvári-Székely
2001
Corpus ID: 16931153
Abstract In the age of high-throughput screening and combinatorial chemistry, the focus of drug discovery is to replace the…
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2000
2000
Solid-phase combinatorial synthesis using MicroKan reactors, Rf tagging, and directed sorting.
X. Xiao
,
R. Li
,
+5 authors
K. Nicolaou
Biotechnology and Bioengineering
2000
Corpus ID: 26668826
A modular system for high-output solid-phase combinatorial synthesis has been designed and developed. The system employs three…
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1998
1998
Multistage accurate mass spectrometry: a "basket in a basket" approach for structure elucidation and its application to a compound from combinatorial synthesis.
Q. Wu
Analytical Chemistry
1998
Corpus ID: 34516529
A "basket in a basket" method based on a multistage accurate mass spectrometric (MAMS) technique was developed and demonstrated…
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