Skip to search formSkip to main contentSkip to account menu

Cobblestone Area-Forming Cells

Known as: CAFC, Cobble Stone Area-Forming Cells, Cobblestone Forming Units 
The number of hematopoietic stem cells (HSCs) that migrate between or beneath a co-cultured feeder cell layer and become trapped. When HSCs are… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Drawing a Line in the Patent Subject-Matter Sands: Does Europe Provide a Solution to the Software and Business Method Patent Problem?
In June 2010, the Supreme Court issued its decision in Bilski v. Kappos, a case that had the potential to rewrite the landscape… 
2009
2009
The obviousness rejection as a barrier to biotech patent prosecution
An analysis of US Federal Circuit decisions shows the effects of the Supreme Court's decision in KSR v. Teleflex. 
Highly Cited
2008
Highly Cited
2008
In vitro assays for cobblestone area-forming cells, LTC-IC, and CFU-C.
Various assays exist that measure the function of hematopoietic stemcells (HSCs). In this chapter, in vitro assays are described… 
Review
2008
Review
2008
Debugging Software Patents: Increasing Innovation and Reducing Uncertainty in the Judicial Reform of Software Patent Law
Software patents not only do no promote innovation, they instead reduce it. The U.S. Executive branch has recommended against… 
2002
2002
Murine stromal cells producing hyper-interleukin-6 and Flt3 ligand support expansion of early human hematopoietic progenitor cells without need of exogenous growth factors
Expansion of primitive hematopoietic progenitor cells (HPC) is a major challenge in stem cell biology. Stimulation by growth… 
Highly Cited
2001
Highly Cited
2001
The dynamics of bone marrow stromal cells in the proliferation of multipotent hematopoietic progenitors by substance P: an understanding of the effects of a neurotransmitter on the differentiating…
1999
1999
Sedimentation and deformation in a Pliocene–Pleistocene transtensional supradetachment basin, Laguna Salada, north‐west Mexico
This study examines a thick section of Pliocene–Pleistocene sedimentary rocks exposed in the footwall of an active normal fault… 
1997
1997
Efficient long-term maintenance of chronic myeloid leukemic cobblestone area forming cells on a murine stromal cell line
Stroma-supported long-term cultures (LTC) of chronic myeloid leukemia (CML) progenitor cells have previously revealed differences… 
1997
1997
Mice lacking a functional CHK gene have no apparent defects in the hematopoietic system
Non‐receptor tyrosine kinase Chk has been implicated in hematopoietic development. To study the function of Chk in vivo, we have… 
1997
1997
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal…
We studied the cell kill induced by granulocyte-macrophage colony-stimulating factor (GM-CSF ) fused to Diphtheria Toxin (DT-GM… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)