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Clostridium perfringens theta-toxin

Known as: pfoA protein, Clostridium perfringens, theta-toxin, Clostridium perfringens, Perfringolysin O 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Bacterial ToxinsHemolysin

Papers overview

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2019
2019
Fine-tuning of the stability of β-strands by Y181 in perfringolysin O directs the prepore to pore transition.
2018
2018
Cholesterol Enriched Archaeosomes as a Molecular System for Studying Interactions of Cholesterol-Dependent Cytolysins with Membranes
Archaeosomes are vesicles made of lipids from archaea. They possess many unique features in comparison to other lipid systems… 
2014
2014
Detection of esterified cholesterol in murine Bruch's membrane wholemounts with a perfringolysin O-based cholesterol marker.
PURPOSE To investigate the effects of Bruch's membrane (BrM) neutral lipid deposition in mouse models and its significance to… 
2014
2014
Engineered pore-forming proteins for the intracellular delivery of macromolecular therapeutics
Macromolecules such as proteins and nucleic acids can potentially be used as powerful therapeutics that reconstitute lost… 
2012
2012
Molecular profiles of cholesterol-dependent cytolysin family-derived 11mer regions.
BACKGROUND Cholesterol-dependent cytolysins (CDCs) are secreted from various types of bacteria and are involved in various… 
Review
2010
Review
2010
[Research progress on the MACPF/CDC family of pore-forming toxins].
Pore-forming toxins (PFTs) are commonly associated with bacterial and other prokaryote pathogenesis. In eukaryotes, PFTs play… 
2007
2007
Irreversible loss of membrane-binding activity of Listeria-derived cytolysins in non-acidic conditions: a distinct difference from allied cytolysins produced by other Gram-positive bacteria.
Listeriolysin O (LLO), a member of the cholesterol-dependent cytolysin (CDC) family, is a major virulence factor of Listeria… 
2004
2004
Structural analysis of human specific cytolysin intermedilysin aiming application to cancer immunotherapy.
BACKGROUND Intermedilysin (ILY) is a human specific cytolysin secreted by Streptococcus intermedius. In the present study, we… 
2003
2003
Characterisation of mouse monoclonal antibodies for pneumolysin: fine epitope mapping and V gene usage.
1995
1995
Efficient gene delivery and expression in mammalian cells using DNA coupled with perfringolysin O.
Current non-viral DNA vectors for gene therapy are limited by low cellular transfection efficiencies and low levels of gene… 
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