Clonal Selection, Antigen-Mediated

Known as: Antigen-Mediated Clonal Selection, Selection, Antigen-Mediated Clonal, Antigen Mediated Clonal Selection 
LYMPHOCYTE ACTIVATION by a specific ANTIGEN thus triggering clonal expansion of LYMPHOCYTES already capable of mounting an immune response to the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
0102019802018

Papers overview

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Highly Cited
2005
Highly Cited
2005
T cell expansion and memory formation are generally more effective when elicited by live organisms than by inactivated vaccines… (More)
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Highly Cited
2005
Highly Cited
2005
The transduction of primary T cells to express chimeric T cell receptors (cTCR) for redirected targeting of tumor cells is an… (More)
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Highly Cited
2003
Highly Cited
2003
Full activation of naive CD8 T cells requires Ag, costimulation, and a third signal that can be provided by IL-12. Brief exposure… (More)
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Highly Cited
2002
Highly Cited
2002
Stimulation of an effective in vitro or in vivo response by naive CD8 T cells requires three signals: TCR engagement… (More)
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Highly Cited
2002
Highly Cited
2002
4-1BB is expressed on activated T cells. We analyzed the role of 4-1BB during the CD8 T cell response of OT-I TCR-transgenic T… (More)
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Highly Cited
2002
Highly Cited
2002
CD28 provides a costimulatory signal that cooperates with the TCR/CD3 complex to induce T cell activation, cytokine production… (More)
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Highly Cited
1998
Highly Cited
1998
The adoptive transfer of naive CD4(+) T cell receptor (TCR) transgenic T cells was used to investigate the mechanisms by which… (More)
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Highly Cited
1997
Highly Cited
1997
Despite the wealth of information on the signals required for T cell activation in vitro, the signals required for the generation… (More)
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Highly Cited
1997
Highly Cited
1997
Antigen receptor engagement on T lymphocytes activates transcription factors important for stimulating cytokine gene expression… (More)
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1997
1997
T cell costimulation, particularly by the B7 family members B7-1 and B7-2, plays a critical role in regulating T cell-mediated… (More)
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