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Clofilium Tosylate

Known as: Benzenebutanaminium, 4-Chloro-N,N-Diethyl-N-Heptyl-, Tosylate 
 
National Institutes of Health

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clofilium

Papers overview

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2017
2017
High-Throughput Drug Screening Identifies Pazopanib and Clofilium Tosylate as Promising Treatments for Malignant Rhabdoid Tumors.
Rhabdoid tumors (RTs) are aggressive tumors of early childhood characterized by SMARCB1 inactivation. Their poor prognosis… Expand
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2016
2016
Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related…
Mitochondria are organelles that have their own DNA (mitochondrial DNA, mtDNA) whose maintenance is necessary for the majority of… Expand
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2013
2013
In vitro assessment of synthetic phenolic antioxidants for inhibition of foodborne Staphylococcus aureus, Bacillus cereus and Pseudomonas fluorescens
Abstract Minimal inhibitory concentrations (MICs) of seven synthetic phenolic compounds, five commonly used as antioxidants (TBHQ… Expand
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2008
2008
Origin of the anomalous X-ray diffraction in phthalocyanine films
The impact of the submolecular electron density on the X-ray diffraction profile of a layer-stacked thin film is studied… Expand
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2005
2005
Effect of aerosil dispersions on the nematic-to-isotropic interface
Abstract.The effect of silica aerosils on the kinetics of the first-order nematic-isotropic (NI) phase transition is… Expand
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1999
1999
Inhibition of herpes simplex virus type 1 and adenovirus type 5 by heterocyclic Schiff bases of aminohydroxyguanidine tosylate 1 Taken in part from the Ph.D dissertation of A. Das, USC, School of…
Abstract Eleven heterocyclic Schiff bases of aminohydroxyguanidine tosylate (SB-AHGs), compounds I–XI, were tested for… Expand
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1999
1999
Electrophysiological characterization of BRL-32872 in canine Purkinje fiber and ventricular muscle. Effect on early after-depolarizations and repolarization dispersion.
Amongst the different pharmacological approaches to the treatment of cardiac arrhythmias, compounds with multiple… Expand
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1997
1997
Contractile effects of porcine galanin(1-29)-NH2 on the rat isolated gastric fundus: mediation by potassium ions.
Galanin (3-300 nM) evoked reproducible concentration-dependent contractions of rat isolated gastric fundus strips, EC50 of the… Expand
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1984
1984
Nasal drug delivery system of a quaternary ammonium compound: clofilium tosylate.
The blood levels of the [14C]clofilium ion in rats after various routes of administration of clofilium tosylate were compared… Expand
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