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Click Chemistry

Known as: Techniques, Click Chemical, Chemical Techniques, Click, Click Chemistries 
Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions… 
National Institutes of Health

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Combinatorial Chemistry Techniquesstandards characteristics

Papers overview

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2016
2016
pH-Responsive Tumor-Targetable Theranostic Nanovectors Based on Core Crosslinked (CCL) Micelles with Fluorescence and Magnetic Resonance (MR) Dual Imaging Modalities and Drug Delivery Performance
The development of novel theranostic nanovectors is of particular interest in treating formidable diseases (e.g., cancers… 
Highly Cited
2014
Highly Cited
2014
Highly selective and ultra fast solid-phase extraction of N-glycoproteome by oxime click chemistry using aminooxy-functionalized magnetic nanoparticles.
For the highly efficient extraction of the N-glycoproteome, a novel solid-phase extraction method based on oxime click chemistry… 
2011
2011
One-pot dual-labeling of a protein by two chemoselective reactions.
Review
2009
Review
2009
Silica-based clicked hybrid glyco materials.
The impact of the copper-mediated alkyne-azide cycloadditions on the covalent click immobilization of carbohydrates onto the… 
2009
2009
Versatile strategy for the synthesis of dendronlike polypeptide/linear poly(epsilon-caprolactone) block copolymers via click chemistry.
A new class of dendron-like polypeptide/linear poly(epsilon-caprolactone) block copolymers with asymmetrical topology (i.e… 
2009
2009
A facile route to prepare organic/inorganic hybrid nanomaterials by 'click chemistry'.
An organosilane with an alkyne group at the non-condensable end, [(2-propynylcarbamate)propyl]triethoxysilane, has been… 
Highly Cited
2007
Highly Cited
2007
ClickFerrophos: new chiral ferrocenyl phosphine ligands synthesized by click chemistry and the use of their metal complexes as catalysts for asymmetric hydrogenation and allylic substitution.
The new ferrocenyl P,P- and P,N-ligands 5 and 6 (collectively, "ClickFerrophos") were readily prepared in four steps using Click… 
2007
2007
Synthesis and evaluation of 1-alkyl-4-phenyl-[1,2,3]-triazole derivatives as antimycobacterial agent
Fourteen small molar mass 1-alkyl-4-phenyl-[1,2,3]-triazole derivatives were prepared using a straightforward and efficient… 
Highly Cited
2007
Highly Cited
2007
A facile synthesis of azido-terminated heterobifunctional poly(ethylene glycol)s for "click" conjugation.
New azido-terminated heterobifunctional poly(ethylene glycol) (PEG) derivatives having primary amine and carboxyl end groups… 
2005
2005
The application of "click chemistry" for the decoration of 2(1H)-pyrazinone scaffold: generation of templates.
The "click chemistry" approach has been explored on the 2-(1H)-pyrazinone scaffold for the generation of pharmacologically… 
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