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Cleavage Stimulation Factor

Known as: Cleavage Stimulation Factor [Chemical/Ingredient], CstF Protein 
A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
In eukaryotes, the 3' ends of RNA polymerase II-transcribed RNAs are generated in the majority of cases by site-specific… Expand
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Highly Cited
2009
Highly Cited
2009
The CDC73 tumor suppressor gene is mutationally inactivated in hereditary and sporadic parathyroid tumors. Its product, the Cdc73… Expand
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Highly Cited
2007
Highly Cited
2007
Polyadenylation, the process of eukaryotic mRNA 3' end formation, is essential for gene expression and cell viability… Expand
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Highly Cited
2005
Highly Cited
2005
Most metazoan messenger RNAs encoding histones are cleaved, but not polyadenylated at their 3' ends. Processing in mammalian cell… Expand
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Highly Cited
2001
Highly Cited
2001
Capping, splicing, and cleavage/polyadenylation of pre-mRNAs are interdependent events that are all stimulated in vivo by the… Expand
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Highly Cited
2000
Highly Cited
2000
Polyadenylation of mRNA precursors is a two-step reaction requiring multiple protein factors. Cleavage stimulation factor (CstF… Expand
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2000
2000
During mRNA 3' end formation, cleavage stimulation factor (CstF) binds to a GU-rich sequence downstream from the polyadenylation… Expand
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Highly Cited
1998
Highly Cited
1998
Cleavage stimulation factor (CstF) is one of the multiple factors required for mRNA polyadenylation. The concentration of one… Expand
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Highly Cited
1996
Highly Cited
1996
Six different protein factors are required for the specific cleavage and polyadenylation of pre-mRNA in mammals. Whereas four of… Expand
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Highly Cited
1996
Highly Cited
1996
The cleavage stimulation factor (CstF), and the cleavage and polyadenylation specificity factor (CPSF) are necessary for 3… Expand
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