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Chronopharmacokinetics

Known as: Chronopharmacokinetic 
Absorption, metabolism and elimination of drugs in relation to time of day at which they are administered, and the mechanisms responsible for time… 
National Institutes of Health

Related topics

Related topics

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Drug Chronotherapy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Circadian variation of gentamicin toxicity in rats
Two undesired effects of the aminoglycoside antibiotic gentamicin are ototoxicity and nephrotoxicity. This study investigated if… 
Highly Cited
2009
Highly Cited
2009
Chronotherapeutic drug delivery for early morning surge in blood pressure: a programmable delivery system.
2003
2003
Chronopharmacokinetics of Tacrolimus in Kidney Transplant Recipients: Occurrence of Acute Rejection
The circadian variation of clinical pharmacokinetics of tacrolimus was studied using 16 adult renal transplant recipients 1 month… 
Review
2002
Review
2002
Clinical pharmacokinetics of 5-fluorouracil with consideration of chronopharmacokinetics
Even though 5-fluorouracil (FU) is one of the oldest anticancer drugs, its use in cancer chemotherapy continues to increase… 
Review
1999
Review
1999
Chronopharmacokinetics: Implications for Drug Treatment
  • B. Lemmer
  • The Journal of pharmacy and pharmacology
  • 1999
  • Corpus ID: 25496626
Nearly all functions of the human body are organized across the 24 hours of the day. This is also true for functions involved in… 
Highly Cited
1999
Highly Cited
1999
Morning versus evening dosing of ibuprofen using conventional and time-controlled release formulations.
Review
1998
Review
1998
Chronopharmacokinetics
Absorption, distribution, metabolism and elimination are influenced by many different physiological functions of the body which… 
Highly Cited
1991
Highly Cited
1991
Chronopharmacokinetics and cardiovascular effects of nifedipine.
Circadian phase dependency in pharmacokinetics and hemodynamic effects on blood pressure and heart rate of different galenic… 
1984
1984
Chronopharmacokinetic Study with Prolonged Infusion of Midazolam
SummaryPhysiological and temporal variation in the disposition of midazolam has been reported. In order to delineate the… 
Review
1982
Review
1982
Circadian Changes of Drug Disposition in Man
SummaryCircadian (≈24 hours) and other endogenous biological rhythms, detectable at all levels of organisation, constitute a… 
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