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Chronopharmacokinetics

Known as: Chronopharmacokinetic 
Absorption, metabolism and elimination of drugs in relation to time of day at which they are administered, and the mechanisms responsible for time… 
National Institutes of Health

Related topics

Related topics

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Drug Chronotherapy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Circadian variation of gentamicin toxicity in rats
Two undesired effects of the aminoglycoside antibiotic gentamicin are ototoxicity and nephrotoxicity. This study investigated if… 
2014
2014
Chronopharmacodynamics and Chronopharmacokinetics of Pethidine in Mice
Background Many studies have demonstrated that the pharmacokinetics and pharmacodynamics of analgesic drugs vary according to the… 
Highly Cited
2009
Highly Cited
2009
Chronotherapeutic drug delivery for early morning surge in blood pressure: a programmable delivery system.
2004
2004
Chronopharmacokinetic study of a prolonged release form of indomethacin
SummaryThe chronopharmacokinetics of indomethacin was studied in patients with rheumatoid diseases after a single oral dose of a… 
1989
1989
Chronopharmacokinetic Study of Valproic Acid in Man: Comparison of Oral and Rectal Administration
Circadian stage‐dependent changes of valproic acid (VPA) kinetics was examined after rectal administration comparing after oral… 
1988
1988
Theophylline-terbutaline, a steady state study on possible pharmacokinetic interactions with special reference to chronopharmacokinetic aspects.
1. The pharmacokinetic interaction of terbutaline and theophylline and chronopharmacokinetics of both drugs were studied in a… 
1987
1987
Chronopharmacokinetics of indomethacin in rats.
In order to establish the origin of the circadian variations in the kinetics of indomethacin (Indocid) observed in humans, a… 
1986
1986
Organ transplantation and broader chronotherapy with lmplantable pump and computer programs for marker rhythm assessment
1984
1984
Chronopharmacokinetic Study with Prolonged Infusion of Midazolam
SummaryPhysiological and temporal variation in the disposition of midazolam has been reported. In order to delineate the… 
Review
1976
Review
1976
Chronopharmacokinetics of ethanol. I. Review of the literature and theoretical considerations.
: Pharmacokinetic parameters are generally assumed to be invariate with the time of day, although circadian variation of drug… 
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