Chronopharmacokinetics

Known as: Chronopharmacokinetic 
Absorption, metabolism and elimination of drugs in relation to time of day at which they are administered, and the mechanisms responsible for time… (More)
National Institutes of Health

Papers overview

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Review
2002
Review
2002
Even though 5-fluorouracil (FU) is one of the oldest anticancer drugs, its use in cancer chemotherapy continues to increase… (More)
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Review
1999
Review
1999
Nearly all functions of the human body are organized across the 24 hours of the day. This is also true for functions involved in… (More)
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Review
1998
Review
1998
Absorption, distribution, metabolism and elimination are influenced by many different physiological functions of the body which… (More)
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1996
1996
Stimulants, in particular the amphetamines, have been studied as countermeasures to fatigue induced by circadian desynchronosis… (More)
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1996
1996
RATIONALE For high-clearance drugs such as nicotine, hemodynamic changes throughout the day may be expected to influence the rate… (More)
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1991
1991
Circadian phase dependency in pharmacokinetics and hemodynamic effects on blood pressure and heart rate of different galenic… (More)
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1991
1991
This study was carried out to investigate the circadian rhythm in the pharmacokinetics of valproic acid (VPA). ICR male mice… (More)
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Review
1989
Review
1989
The pharmacokinetic parameters of drugs vary largely and predictably as a function of their dosing time along the 24-hr scale… (More)
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1987
1987
In order to establish the origin of the circadian variations in the kinetics of indomethacin (Indocid) observed in humans, a… (More)
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1985
1985
The chronopharmacokinetics of paracetamol was studied in six male volunteers. Serum concentrations of paracetamol were determined… (More)
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