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Chronic granulomatous disease
Known as:
Chronic Granulomatous Diseases
, Granulomatous Diseases, Chronic
, CGD
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A rare genetic disorder with a predominantly X-linked recessive pattern of inheritance resulting in impaired phagocytic clearance of bacteria and…
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National Institutes of Health
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Related topics
Related topics
15 relations
Chronic disease
FMN reductase
Granulomatous Disease, Chronic, X-Linked
In Blood
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Narrower (3)
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Negative
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type I
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type II
Broader (1)
Phagocyte Bactericidal Dysfunction
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Advances in Burkholderia cepacia complex.
D. Speert
Paediatric Respiratory Reviews
2002
Corpus ID: 30067004
Highly Cited
1998
Highly Cited
1998
Modulation of human neutrophil apoptosis by immune complexes.
R. Gamberale
,
Mirta Giordano
,
A. Trevani
,
G. Andonegui
,
J. Geffner
Journal of Immunology
1998
Corpus ID: 23470238
In the present study we examined whether immune complexes (IC) are able to modulate human neutrophil apoptosis. We observed…
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Highly Cited
1994
Highly Cited
1994
A new flow cytometric assay for the evaluation of phagocytosis and the oxidative burst in whole blood.
S. Perticarari
,
G. Presani
,
E. Banfi
JIM - Journal of Immunological Methods
1994
Corpus ID: 27574508
Highly Cited
1991
Highly Cited
1991
Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease.
B. Bolscher
,
M. Boer
,
A. Klein
,
R. S. Weening
,
D. Roos
Blood
1991
Corpus ID: 38533504
The NADPH:O2 oxidoreductase of phagocytic leukocytes is an important enzyme for the bactericidal activity of these cells…
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Highly Cited
1987
Highly Cited
1987
Activation of the respiratory burst oxidase in a fully soluble system from human neutrophils.
J. Curnutte
,
R. Kuver
,
B. Babior
Journal of Biological Chemistry
1987
Corpus ID: 43401842
Highly Cited
1984
Highly Cited
1984
B cell lines as models for inherited phagocytic diseases: abnormal superoxide generation in chronic granulomatous disease and giant granules in Chediak-Higashi syndrome.
D. Volkman
,
E. Buescher
,
J. Gallin
,
A. Fauci
Journal of Immunology
1984
Corpus ID: 41764411
Epstein Barr virus (EBV)-transformed B cell lines (BCL) were developed from peripheral blood lymphocytes of individuals with…
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Highly Cited
1982
Highly Cited
1982
Functional relationship of the cytochrome b to the superoxide-generating oxidase of human neutrophils.
T. Gabig
,
E. Schervish
,
J. T. Santinga
Journal of Biological Chemistry
1982
Corpus ID: 5958837
Highly Cited
1976
Highly Cited
1976
The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes
R. Baehner
,
L. Boxer
,
Jacqueline Davis
1976
Corpus ID: 208177930
Normal human polymorphonuclear leukocytes (PMN) placed in anaerobic chambers reaching pO2's of less than 5 mm Hg fail to generate…
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Highly Cited
1971
Highly Cited
1971
Nitroblue‐Tetrazolium Test for the Detection of Chronic Granulomatous Disease—Technical Modification
E. Preisig
,
W. Hitzig
European Journal of Clinical Investigation
1971
Corpus ID: 26542505
Abstract. A new modification of the nitroblue‐tetrazolium (NBT) test for the detection of chronic granulomatous disease is…
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Highly Cited
1968
Highly Cited
1968
Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood: bactericidal capacity for streptococci.
Edward L. Kaplan
,
Throstur Laxdal
,
P. G. Quie
Pediatrics
1968
Corpus ID: 33374644
Polymorphonuclear leukocytes (PMNs) from children with chronic granulomatous disease of childhood have been shown to readily…
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