Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Chronic granulomatous disease

Known as: Chronic Granulomatous Diseases, Granulomatous Diseases, Chronic, CGD 
A rare genetic disorder with a predominantly X-linked recessive pattern of inheritance resulting in impaired phagocytic clearance of bacteria and… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Gene-modified autologous hematopoietic stem cells (HSC) can provide ample clinical benefits to subjects suffering from X-linked… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Gene transfer into hematopoietic stem cells has been used successfully for correcting lymphoid but not myeloid immunodeficiencies… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
A registry of United States residents with chronic granulomatous disease (CGD) was established in 1993 in order to estimate the… Expand
Is this relevant?
Review
2000
Review
2000
The reduced nicotinamide dinucleotide phosphate (NADPH) oxidase complex allows phagocytes to rapidly convert O2 to superoxide… Expand
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Chronic granulomatous disease (CGD) is a recessive disorder characterized by a defective phagocyte respiratory burst oxidase… Expand
Is this relevant?
Highly Cited
1991
Highly Cited
1991
BACKGROUND Chronic granulomatous disease is an uncommon inherited disorder of phagocytes in which defective production of the… Expand
Is this relevant?
Highly Cited
1986
Highly Cited
1986
The gene that is abnormal in the X-linked form of the phagocytic disorder chronic granulomatous disease has been cloned without… Expand
Is this relevant?
Highly Cited
1968
Highly Cited
1968
Abstract Chronic granulomatous disease is an X-linked defect in the killing of certain bacteria by peripheral blood granulocytes… Expand
Is this relevant?
Highly Cited
1967
Highly Cited
1967
Diminished bactericidal capacity was found to be characteristic of polymorphonuclear leukocytes (PMN) from five children with the… Expand
  • table I
  • table II
  • figure 1
  • table III
  • figure 2
Is this relevant?