Chronic granulomatous disease

Known as: Chronic Granulomatous Diseases, Granulomatous Diseases, Chronic, CGD 
A rare genetic disorder with a predominantly X-linked recessive pattern of inheritance resulting in impaired phagocytic clearance of bacteria and… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Chronic granulomatous disease (CGD) is a paradigm for nonlymphoid primary immune defects, and has guided elucidation of oxygen… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Gene-modified autologous hematopoietic stem cells (HSC) can provide ample clinical benefits to subjects suffering from X-linked… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Half a century ago, chronic granulomatous disease (CGD) was first described as a disease fatally affecting the ability of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2008
Review
2008
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder of phagocytic cells resulting in failure to kill… (More)
  • figure 1
  • table I
  • table II
  • table III
Is this relevant?
Highly Cited
2005
Highly Cited
2005
A 2(1/2)-year-old child presented with multiple discrete granulomatous lesions on the face and flexural regions since the age of… (More)
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
A registry of United States residents with chronic granulomatous disease (CGD) was established in 1993 in order to estimate the… (More)
Is this relevant?
Review
2000
Review
2000
The reduced nicotinamide dinucleotide phosphate (NADPH) oxidase complex allows phagocytes to rapidly convert O2 to superoxide… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Chronic granulomatous disease (CGD) is a recessive disorder characterized by a defective phagocyte respiratory burst oxidase… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Chronic granulomatous disease (CGD) is caused by a congenital defect in phagocyte reduced nicotinamide dinucleotide phosphate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?