Chronic granulomatous disease

Known as: Chronic Granulomatous Diseases, Granulomatous Diseases, Chronic, CGD 
A rare genetic disorder with a predominantly X-linked recessive pattern of inheritance resulting in impaired phagocytic clearance of bacteria and… (More)
National Institutes of Health

Related topics

Related topics

15 relations
Chronic diseaseFMN reductaseGranulomatous Disease, Chronic, X-LinkedIn Blood
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Narrower (3)

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-NegativeGranulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type IGranulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type II

Broader (1)

Phagocyte Bactericidal Dysfunction

Papers overview

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Review
2013
Review
2013
Chronic granulomatous disease.
Chronic granulomatous disease (CGD) is a paradigm for nonlymphoid primary immune defects, and has guided elucidation of oxygen… (More)
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Highly Cited
2010
Highly Cited
2010
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
Gene-modified autologous hematopoietic stem cells (HSC) can provide ample clinical benefits to subjects suffering from X-linked… (More)
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Highly Cited
2009
Highly Cited
2009
Chronic Granulomatous Disease: The European Experience
CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex… (More)
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Highly Cited
2008
Highly Cited
2008
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease
Half a century ago, chronic granulomatous disease (CGD) was first described as a disease fatally affecting the ability of… (More)
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Review
2008
Review
2008
Modern management of chronic granulomatous disease.
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder of phagocytic cells resulting in failure to kill… (More)
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Highly Cited
2005
Highly Cited
2005
Chronic granulomatous disease.
A 2(1/2)-year-old child presented with multiple discrete granulomatous lesions on the face and flexural regions since the age of… (More)
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Highly Cited
2000
Highly Cited
2000
Chronic granulomatous disease. Report on a national registry of 368 patients.
A registry of United States residents with chronic granulomatous disease (CGD) was established in 1993 in order to estimate the… (More)
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Review
2000
Review
2000
Genetic, biochemical, and clinical features of chronic granulomatous disease.
The reduced nicotinamide dinucleotide phosphate (NADPH) oxidase complex allows phagocytes to rapidly convert O2 to superoxide… (More)
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Highly Cited
1995
Highly Cited
1995
Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
Chronic granulomatous disease (CGD) is a recessive disorder characterized by a defective phagocyte respiratory burst oxidase… (More)
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Highly Cited
1995
Highly Cited
1995
The p47phox mouse knock-out model of chronic granulomatous disease
Chronic granulomatous disease (CGD) is caused by a congenital defect in phagocyte reduced nicotinamide dinucleotide phosphate… (More)
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