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Chronic granulomatous disease

Known as: Chronic Granulomatous Diseases, Granulomatous Diseases, Chronic, CGD 
A rare genetic disorder with a predominantly X-linked recessive pattern of inheritance resulting in impaired phagocytic clearance of bacteria and… 
National Institutes of Health

Related topics

Related topics

15 relations
Chronic diseaseFMN reductaseGranulomatous Disease, Chronic, X-LinkedIn Blood

Narrower (3)

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-NegativeGranulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type IGranulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type II

Broader (1)

Phagocyte Bactericidal Dysfunction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Advances in Burkholderia cepacia complex.
Highly Cited
1998
Highly Cited
1998
Modulation of human neutrophil apoptosis by immune complexes.
In the present study we examined whether immune complexes (IC) are able to modulate human neutrophil apoptosis. We observed… 
Highly Cited
1994
Highly Cited
1994
A new flow cytometric assay for the evaluation of phagocytosis and the oxidative burst in whole blood.
Highly Cited
1991
Highly Cited
1991
Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease.
The NADPH:O2 oxidoreductase of phagocytic leukocytes is an important enzyme for the bactericidal activity of these cells… 
Highly Cited
1987
Highly Cited
1987
Activation of the respiratory burst oxidase in a fully soluble system from human neutrophils.
Highly Cited
1984
Highly Cited
1984
B cell lines as models for inherited phagocytic diseases: abnormal superoxide generation in chronic granulomatous disease and giant granules in Chediak-Higashi syndrome.
Epstein Barr virus (EBV)-transformed B cell lines (BCL) were developed from peripheral blood lymphocytes of individuals with… 
Highly Cited
1982
Highly Cited
1982
Functional relationship of the cytochrome b to the superoxide-generating oxidase of human neutrophils.
Highly Cited
1976
Highly Cited
1976
The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes
Normal human polymorphonuclear leukocytes (PMN) placed in anaerobic chambers reaching pO2's of less than 5 mm Hg fail to generate… 
Highly Cited
1971
Highly Cited
1971
Nitroblue‐Tetrazolium Test for the Detection of Chronic Granulomatous Disease—Technical Modification
Abstract. A new modification of the nitroblue‐tetrazolium (NBT) test for the detection of chronic granulomatous disease is… 
Highly Cited
1968
Highly Cited
1968
Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood: bactericidal capacity for streptococci.
Polymorphonuclear leukocytes (PMNs) from children with chronic granulomatous disease of childhood have been shown to readily… 
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