Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Chronic granulomatous disease

Known as: Chronic Granulomatous Diseases, Granulomatous Diseases, Chronic, CGD 
A rare genetic disorder with a predominantly X-linked recessive pattern of inheritance resulting in impaired phagocytic clearance of bacteria and… Expand
National Institutes of Health

Related topics

Related topics

15 relations
Chronic diseaseFMN reductaseGranulomatous Disease, Chronic, X-LinkedIn Blood
Expand

Narrower (3)

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-NegativeGranulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type IGranulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type II

Broader (1)

Phagocyte Bactericidal Dysfunction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
Gene-modified autologous hematopoietic stem cells (HSC) can provide ample clinical benefits to subjects suffering from X-linked… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Chronic Granulomatous Disease: The European Experience
CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
Gene transfer into hematopoietic stem cells has been used successfully for correcting lymphoid but not myeloid immunodeficiencies… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Chronic Granulomatous Disease: Report on a National Registry of 368 Patients
A registry of United States residents with chronic granulomatous disease (CGD) was established in 1993 in order to estimate the… Expand
Is this relevant?
Review
2000
Review
2000
Genetic, biochemical, and clinical features of chronic granulomatous disease.
The reduced nicotinamide dinucleotide phosphate (NADPH) oxidase complex allows phagocytes to rapidly convert O2 to superoxide… Expand
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
Chronic granulomatous disease (CGD) is a recessive disorder characterized by a defective phagocyte respiratory burst oxidase… Expand
Is this relevant?
Highly Cited
1991
Highly Cited
1991
A controlled trial of interferon gamma to prevent infection in chronic granulomatous disease. The International Chronic Granulomatous Disease Cooperative Study Group.
BACKGROUND Chronic granulomatous disease is an uncommon inherited disorder of phagocytes in which defective production of the… Expand
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location
The gene that is abnormal in the X-linked form of the phagocytic disorder chronic granulomatous disease has been cloned without… Expand
Is this relevant?
Highly Cited
1968
Highly Cited
1968
Quantitative nitroblue tetrazolium test in chronic granulomatous disease.
Abstract Chronic granulomatous disease is an X-linked defect in the killing of certain bacteria by peripheral blood granulocytes… Expand
Is this relevant?
Highly Cited
1967
Highly Cited
1967
In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood.
Diminished bactericidal capacity was found to be characteristic of polymorphonuclear leukocytes (PMN) from five children with the… Expand
  • table I
  • table II
  • figure 1
  • table III
  • figure 2
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE