Skip to search formSkip to main contentSkip to account menu

Chromosome Breakpoints

Known as: Breakpoint, Chromosome, Breakpoints, Chromosome, Chromosome Breakpoint 
The locations in specific DNA sequences where CHROMOSOME BREAKS have occurred.
National Institutes of Health

Related topics

Related topics

1 relation
aspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.
Highly Cited
2005
Highly Cited
2005
Position effects due to chromosome breakpoints that map approximately 900 Kb upstream and approximately 1.3 Mb downstream of SOX9 in two patients with campomelic dysplasia.
Campomelic dysplasia (CD) is a semilethal skeletal malformation syndrome with or without XY sex reversal. In addition to the… 
Highly Cited
2004
Highly Cited
2004
A Recurrent Chromosome Breakpoint in Breast Cancer at the NRG1/Neuregulin 1/Heregulin Gene
Most studies of genomic rearrangements in common cancers have focused on regional gains and losses, but some rearrangements may… 
Highly Cited
2000
Highly Cited
2000
Intronic U50 small‐nucleolar‐RNA (snoRNA) host gene of no protein‐coding potential is mapped at the chromosome breakpoint t(3;6)(q27;q15) of human B‐cell lymphoma
In eukaryotic cells, nucleolar processing of preribosomal RNAs (prerRNAs) is assisted by a large number of small nucleolar RNAs… 
Highly Cited
1999
Highly Cited
1999
Chromosome abnormalities in ovarian adenocarcinoma: I. nonrandom chromosome abnormalities from 244 cases
Cytogenetics provides important insights into the molecular pathogenesis of human cancers. Although extensive data exist on… 
Highly Cited
1994
Highly Cited
1994
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
Human synovial sarcomas contain a recurrent and specific chromosomal translocation t(X;18)(p11.2;q11.2). By screening a synovial… 
Highly Cited
1992
Highly Cited
1992
Cloning and characterization of chromosome breakpoints of Plasmodium falciparum: breakage and new telomere formation occurs frequently and randomly in subtelomeric genes.
We analysed the genetic stability of two subtelomeric genes of the human malaria parasite Plasmodium falciparum. A PCR based… 
Highly Cited
1988
Highly Cited
1988
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.
Achieving the capacity to detect minimal numbers of neoplastic cells is a major cancer diagnostic challenge. Chromosomal… 
Highly Cited
1986
Highly Cited
1986
Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.
In chronic myelogenous leukemias (CML) with the t(9;22)(q34;q11) chromosome translocation the breakpoints on chromosome 22 occur… 
Highly Cited
1984
Highly Cited
1984
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation.
From an acute B-cell leukemia cell line, a DNA probe was obtained that was specific for chromosome 18 and flanked the heavy chain… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)