Chromosome Breakpoints

Known as: Breakpoint, Chromosome, Breakpoints, Chromosome, Chromosome Breakpoint 
The locations in specific DNA sequences where CHROMOSOME BREAKS have occurred.
National Institutes of Health

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aspects of radiation effects

Papers overview

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2017
2017
Upgrading short-read animal genome assemblies to chromosome level using comparative genomics and a universal probe set.
Most recent initiatives to sequence and assemble new species' genomes de novo fail to achieve the ultimate endpoint to produce… (More)
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2007
2007
Rapid high-resolution karyotyping with precise identification of chromosome breakpoints.
Many techniques have been developed in recent years for genome-wide analysis of genetic alterations, but no current approach is… (More)
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Highly Cited
2005
Highly Cited
2005
Position effects due to chromosome breakpoints that map approximately 900 Kb upstream and approximately 1.3 Mb downstream of SOX9 in two patients with campomelic dysplasia.
Campomelic dysplasia (CD) is a semilethal skeletal malformation syndrome with or without XY sex reversal. In addition to the… (More)
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2000
2000
Intronic U50 small-nucleolar-RNA (snoRNA) host gene of no protein-coding potential is mapped at the chromosome breakpoint t(3;6)(q27;q15) of human B-cell lymphoma.
BACKGROUND In eukaryotic cells, nucleolar processing of preribosomal RNAs (prerRNAs) is assisted by a large number of small… (More)
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Highly Cited
1994
Highly Cited
1994
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
Human synovial sarcomas contain a recurrent and specific chromosomal translocation t(X;18)(p11.2;q11.2). By screening a synovial… (More)
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Highly Cited
1988
Highly Cited
1988
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.
Achieving the capacity to detect minimal numbers of neoplastic cells is a major cancer diagnostic challenge. Chromosomal… (More)
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1988
1988
Regional chromosome localization of human papillomavirus integration sites near fragile sites, oncogenes, and cancer chromosome breakpoints.
The integration sites of human papillomavirus (HPV) DNA within the cervical carcinoma cell line C4-I and a primary cervical tumor… (More)
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1986
1986
Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.
In chronic myelogenous leukemias (CML) with the t(9;22)(q34;q11) chromosome translocation the breakpoints on chromosome 22 occur… (More)
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Highly Cited
1984
Highly Cited
1984
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation.
From an acute B-cell leukemia cell line, a DNA probe was obtained that was specific for chromosome 18 and flanked the heavy chain… (More)
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1984
1984
Cancer chromosome breakpoints and common fragile sites induced by aphidicolin.
A new class of fragile sites termed common fragile sites is induced by aphidicolin, an inhibitor of DNA polymerase alpha… (More)
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