Chromosome abnormalities in ovarian adenocarcinoma: I. Nonrandom chromosome abnormalities from 244 cases.

@article{Taetle1999ChromosomeAI,
  title={Chromosome abnormalities in ovarian adenocarcinoma: I. Nonrandom chromosome abnormalities from 244 cases.},
  author={Raymond Taetle and Mikel Aickin and Jin M in Yang and Luzizila Helena Panda and J. Terry Emerson and Dusten Roe and Laskus Adair and Fabiano Lopes Thompson and Youlin Liu and Lee Wisner and Jeffrey R. Davis and Jeffrey M. Trent and David S. Alberts},
  journal={Genes, chromosomes & cancer},
  year={1999},
  volume={25 3},
  pages={
          290-300
        }
}
Cytogenetics provides important insights into the molecular pathogenesis of human cancers. Although extensive data exist on recurring cytogenetic abnormalities in hematologic cancers, data on individual solid tumor types remain limited. Previous studies of ovarian carcinoma indicated the presence of multiple, complex clonal chromosome abnormalities. Cytogenetics remains one of a few techniques capable of detecting these multiple, simultaneously occurring genetic abnormalities. We describe… CONTINUE READING

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