Skip to search formSkip to main contentSkip to account menu

Chromosome Breakage

Known as: establishment or maintenance of heterochromatin architecture, Breakage, Chromosomal, High frequency of chromosome breaks in lymphocytes 
Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (2)

Chromosome BreaksTHROMBOCYTOPENIA 2 (disorder)
Chromosome FragilityChromosome breakage:ACnc:Pt:Bld:Qn:DiepoxybutaneChromosome breakage:Imp:Pt:XXX:NomChromosome breakage:Prid:Pt:Bld:Nar:Diepoxybutane

Broader (1)

programmed DNA elimination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Preferential location of x-ray induced chromosome breakage in the R-bands of human chromosomes.
The distribution of chromosome breakage points along human chromosomes was studied in lymphocytes irradiated in the G0-period… 
Highly Cited
2003
Highly Cited
2003
Induction of genome instability by DNA damage in Saccharomyces cerevisiae.
Highly Cited
1996
Highly Cited
1996
Spontaneous and radiation-induced chromosomal breakage at interstitial telomeric sites
The Chinese hamster genome contains a total of 18 cytologically detectable arrays of interstitial telometic sequences. A… 
Highly Cited
1990
Highly Cited
1990
Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints.
Highly Cited
1986
Highly Cited
1986
Chromosomal rearrangements, genes, and fragile sites in cancer: clinical and biologic implications.
Highly Cited
1986
Highly Cited
1986
Cytogenetic and immunophenotypic analysis of cell lines established from patients with T cell leukemia/lymphoma.
Cell lines were established from five patients with T cell malignancies. Two patients had T cell lymphoblastic lymphoma (T-LL… 
Highly Cited
1984
Highly Cited
1984
Genetic damage in CHO cells exposed to enzymically generated active oxygen species.
Highly Cited
1976
Highly Cited
1976
Identification with G and R banding of the position of breakage points induced in human chromosomes by in vitro x-irradiation.
The aberrations seen in chromosomes of human peripheral-blood lymphocytes, X-irradiated in vitro, have been analysed in three… 
Highly Cited
1965
Highly Cited
1965
Effects of ultraviolet radiation on mammalian cells. I. Induction of chromosome aberrations.
Highly Cited
1962
Highly Cited
1962
EFFECTS OF FLUORODEOXYURIDINE ON DNA REPLICATION, CHROMOSOME BREAKAGE, AND REUNION.
t Fulbright grantee 1960-62. 1 Helinski, D. R., and C. Yanofsky, these PROCEEDINGS, 48, 173 (1962). 2 Maling, B. D., and C… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)