Chromomycin
National Institutes of Health
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We have studied the effects of chromomycin and of a triple-helix-forming oligonucleotide (TFO) that recognizes Sp1 binding sites…
Previous structural studies on the complexes of the chromomycin (CHR) dimer with duplexes of d(A1-A2-G3-G4-C5-C6-T7-T8) and of d…
The structure of the chromomycin-DNA complex at the deoxyoctanucleotide duplex level has been determined from one- and two…
The intelligent design of new families of DNA-binding antitumour agents must await an understanding at the molecular level of the…
1H and 31P NMR spectral analysis of a chromomycin/d(ATGCAT)2 complex provides strong evidence for a nonintercalative mode of drug…
The circular dichroism spectra of complexes of the antibiotics daunomycin, nogalamycin, chromomycin, and mithramycin with calf…
IT has been reported that chromomycin A3, a new antitumour agent produced by Streptomyces griseus No. 7, has inhibitory effects…