Chondroitin Sulfate Proteoglycans

In the adult mammalian CNS, chondroitin sulfate proteoglycans (CSPGs) and myelin-associated inhibitors (MAIs) stabilize neuronal… Expand

Toward Neuronal Regeneration Neurons in the central nervous system that are severed or crushed do not regenerate well. Part of… Expand

Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan (GAG) chains. There is enormous… Expand

Inhibitory molecules associated with myelin and the glial scar limit axon regeneration in the adult central nervous system (CNS… Expand

The response of neuronal growth cones to axon guidance cues depends on the developmental context in which these cues are… Expand

Chondroitin sulfate proteoglycans (CSPGs) are extracellular matrix (ECM) molecules that are widely expressed throughout the… Expand

Axons fail to regenerate in the central nervous system after injury. Chondroitin sulfate proteoglycans (CSPG) expressed in the… Expand

Several extracellular matrix (ECM) molecules have been identified as potent inhibitors of neurite outgrowth in vitro and are… Expand

Chondroitin sulfate proteoglycans (CS-PGs) expressed by reactive astrocytes may contribute to the axon growth-inhibitory… Expand

The chondroitin sulfate proteoglycans (CSPGs) have been implicated as both positive and negative modulators of axonal growth… Expand