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Cholestyramine Resin

Known as: Colestyramins, Cholestyramine Resin [Chemical/Ingredient], Colestyramin 
An anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble… 
National Institutes of Health

Related topics

Related topics

26 relations

Broader (4)

Anion Exchange ResinsAnticholesteremic AgentsAntilipemic agentQuaternary Ammonium Compounds
Binding Activity [MoA]Cholestasis, ExtrahepaticCholestyramine Resin 4000 MG Powder for Oral SuspensionCoronary Artery Disease

Narrower (6)

CuemidMK-135PrevaliteQuantalan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2000
Review
2000
APO E gene and gene-environment effects on plasma lipoprotein-lipid levels.
Apolipoprotein E (apo E) is important in plasma lipid metabolism and is a component of several plasma lipoprotein-lipid particles… 
Highly Cited
1991
Highly Cited
1991
Comparison of CI-976, an ACAT inhibitor, and selected lipid-lowering agents for antiatherosclerotic activity in iliac-femoral and thoracic aortic lesions. A biochemical, morphological, and…
Due to the potential importance of acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) in the generation of lipid-filled… 
Highly Cited
1983
Highly Cited
1983
Reduction of serum cholesterol in heterozygous patients with familial hypercholesterolemia. Additive effects of compactin and cholestyramine.
We studied the effects of the bile acid sequestrant cholestyramine, alone and in combination with the experimental agent… 
Highly Cited
1982
Highly Cited
1982
Correlation of low and high density lipoprotein binding in vivo with rates of lipoprotein degradation in the rat. A comparison of lipoproteins of rat and human origin.
Highly Cited
1980
Highly Cited
1980
Effects of cholestyramine on receptor-mediated plasma clearance and tissue uptake of human low density lipoproteins in the rabbit.
Highly Cited
1979
Highly Cited
1979
Effect of diosgenin on lipid metabolism in rats.
The purpose of this study was to determine whether diosgenin suppresses cholesterol absorption in rats, and to examine relevant… 
Highly Cited
1978
Highly Cited
1978
Rat-liver acyl-CoA: cholesterol acyltransferase.
The activity of acyl-CoA:cholesterol acyltransferase was measured in rat-liver microsomes from the rate of incorporation of [1… 
Highly Cited
1974
Highly Cited
1974
Effect of alterations of the specific activity of the intracellular acetyl CoA pool on apparent rates of hepatic cholesterogenesis.
We have previously shown significant dilution of the specific activity of the intracellular acetyl CoA pool when radiolabeled… 
Highly Cited
1972
Highly Cited
1972
HMG CoA reductase of intestinal mucosa and liver of the rat.
Methods were developed for the determination of HMG CoA (3-hydroxy-3-methylglutaryl CoA) reductase activity in subcellular… 
Highly Cited
1968
Highly Cited
1968
7α-Hydroxylation of cholestanol by rat liver microsomes
: In a study of the mechanism whereby 5alpha-bile acids are formed from cholestanol, the 7alpha-hydroxylation of cholestanol was… 
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