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Cholestasis, Extrahepatic

Known as: Extrahepatic cholestasis, Extrahepatic Biliary Stasis, Cholestasis, Extrahepatic [Disease/Finding] 
Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.
National Institutes of Health

Related topics

Related topics

17 relations

Broader (1)

Cholestasis
Cholestyramine ResinCholestyramine Resin 4000 MG Powder for Oral SuspensionClavulanateColesevelam hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis.
BACKGROUND & AIMS Cholestasis is a liver disorder characterized by impaired bile flow, reduction of bile acids (BAs) in the… 
Highly Cited
2006
Highly Cited
2006
Impact of classification of hilar cholangiocarcinomas (Klatskin tumors) on the incidence of intra- and extrahepatic cholangiocarcinoma in the United States.
Cholangiocarcinomas are topographically categorized as intrahepatic or extrahepatic by the International Classification of… 
Review
2006
Review
2006
Hepatic metastases: diffusion-weighted sensitivity-encoding versus SPIO-enhanced MR imaging.
PURPOSE To retrospectively compare accuracy of diffusion-weighted (DW) single-shot echo-planar imaging with sensitivity encoding… 
Highly Cited
2003
Highly Cited
2003
Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor… 
Highly Cited
2001
Highly Cited
2001
Effect of Preoperative Biliary Decompression on Pancreaticoduodenectomy-Associated Morbidity in 300 Consecutive Patients
ObjectiveTo examine the relationship between preoperative biliary drainage and the morbidity and mortality associated with… 
Highly Cited
1999
Highly Cited
1999
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.
Highly Cited
1998
Highly Cited
1998
Expression of the UDP-glucuronosyltransferase 1A Locus in Human Colon
UDP-glucuronosyltransferases (UGT) catalyze the conjugation of lipophilic exobiotic and endobiotic compounds, which leads to the… 
Highly Cited
1993
Highly Cited
1993
Group A Rotaviruses Produce Extrahepatic Biliary Obstruction in Orally Inoculated Newborn Mice
ABSTRACT: Extrahepatic biliary atresia is a devastating disease occurring in 1 in 10 000 to 14 000 infants annually in the United… 
Highly Cited
1988
Highly Cited
1988
Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules.
To establish the role of the biliary epithelium in bile formation, we studied several aspects of biliary physiology in control… 
Highly Cited
1982
Highly Cited
1982
Cholecystectomy in cirrhotic patients: a formidable operation.
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