Cholesterol 7-alpha-Monooxygenase

Known as: Cytochrome P-450 CYP7, Cholesterol 7-alpha-Hydroxylase, Cholesterol-7-Hydroxylase 
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The liver and intestine play crucial roles in maintaining bile acid homeostasis. Here, we demonstrate that fibroblast growth… (More)
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Highly Cited
2005
Highly Cited
2005
Thyroid hormones [predominantly 3,5,3'-triiodo-L-thyronine (T3)] regulate cholesterol and lipoprotein metabolism, but cardiac… (More)
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Highly Cited
2003
Highly Cited
2003
Guggulipid is an extract of the guggul tree Commiphora mukul and has been widely used to treat hyperlipidemia in humans. The… (More)
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Review
2002
Review
2002
Bile acids derived from cholesterol and oxysterols derived from cholesterol and bile acid synthesis pathways are signaling… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND There are two main stimuli that entrain the circadian rhythm, the light-dark cycle (LD) and restricted feeding (RF… (More)
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Highly Cited
2000
Highly Cited
2000
Mice lacking the nuclear bile acid receptor FXR/BAR developed normally and were outwardly identical to wild-type littermates. FXR… (More)
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Highly Cited
2000
Highly Cited
2000
The catabolism of cholesterol into bile acids is regulated by oxysterols and bile acids, which induce or repress transcription of… (More)
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Highly Cited
1999
Highly Cited
1999
Bile acids are essential for the solubilization and transport of dietary lipids and are the major products of cholesterol… (More)
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Highly Cited
1998
Highly Cited
1998
We demonstrate that mice lacking the oxysterol receptor, LXR alpha, lose their ability to respond normally to dietary cholesterol… (More)
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Highly Cited
1997
Highly Cited
1997
Accumulation of cholesterol causes both repression of genes controlling cholesterol biosynthesis and cellular uptake and… (More)
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