CYP7A1 protein, human

Known as: Cholesterol 7-Alpha-Hydroxylase, Cytochrome P450 Family 7 Subfamily A Polypeptide 1, cholesterol-7-alpha-hydroxylase, human 
Cholesterol 7-alpha-monooxygenase (504 aa, ~58 kDa) is encoded by the human CYP7A1 gene. This protein plays a role in both cholesterol catabolism and… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Bile acids are physiological detergents that generate bile flow and facilitate intestinal absorption and transport of lipids… (More)
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Highly Cited
2004
Highly Cited
2004
Moderate consumption of red wine reduces risk of death from cardiovascular disease. The polyphenols in red wine are ultimately… (More)
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Highly Cited
2003
Highly Cited
2003
In rodent liver, transcription of the gene encoding cholesterol 7alpha-hydroxylase (CYP7A1), which catalyzes the rate-limiting… (More)
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Highly Cited
2002
Highly Cited
2002
Bile acid synthesis plays a critical role in the maintenance of mammalian cholesterol homeostasis. The CYP7A1 gene encodes the… (More)
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2002
2002
Cholesterol 7 alpha-hydroxylase (CYP7A1) catalyzes the rate-limiting step in the classic pathway of bile acid biosynthesis… (More)
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Highly Cited
2001
Highly Cited
2001
Cholesterol 7alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in the neutral pathway of bile acid biosynthesis, is feedback… (More)
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2001
2001
The cholesterol 7alpha-hydroxylase gene (CYP7A1) plays an important role in regulation of bile acid biosynthesis and cholesterol… (More)
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Highly Cited
2000
Highly Cited
2000
The catabolism of cholesterol into bile acids is regulated by oxysterols and bile acids, which induce or repress transcription of… (More)
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Highly Cited
2000
Highly Cited
2000
Bile acids repress the transcription of cytochrome P450 7A1 (CYP7A1), which catalyzes the rate-limiting step in bile acid… (More)
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Highly Cited
2000
Highly Cited
2000
Cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription is repressed by bile acids. The goal of this study is to elucidate the… (More)
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