Skip to search formSkip to main contentSkip to account menu

Chlorotoxin

Known as: CTX 
A neurotoxin with potential anticancer property. Chlorotoxin (CTX) is a 36-amino acid peptide found in the venom of the deathstalker scorpion, and a… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

131-I-TM-601TM-601
CyclophosphamideNCIt Antineoplastic Agent Terminology

Broader (1)

Scorpion Venoms

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Fabrication of magnetic nanochains linked with CTX and curcumin for dual modal imaging detection and limitation of early tumour
Five‐year survival rate at early lung tumour was about 70%; however, its early diagnosis rate was still at a low level, so the… 
2018
2018
The comprehensive electrophysiological study of curcuminoids on delayed‐rectifier K+ currents in insulin‐secreting cells
2016
2016
Functionalized magnetic nanochains with enhanced MR imaging: A novel nanosystem for targeting and inhibition of early glioma.
2016
2016
A phase I evaluation of intravenous (IV) 131I-chlorotoxin delivery to solid peripheral and intracranial tumors.
e14507 Background: Pre-clinical studies demonstrate TM601 binding to glioblastoma, melanoma, and other tumor types in vitro and… 
Review
2015
Review
2015
Chlorotoxin-conjugated nanoparticles for targeted imaging and therapy of glioma.
This review reports the recent advances in chlorotoxin (CTX)-targeted nanoparticles (NPs) for imaging and therapy of glioma. CTX… 
Highly Cited
2011
Highly Cited
2011
Chlorotoxin-modified macromolecular contrast agent for MRI tumor diagnosis.
2007
2007
Differential pharmacology of the cardiac anionic background current I(AB).
2006
2006
Imaging and nanomedicine for diagnosis and therapy in the central nervous system: report of the eleventh annual Blood-Brain Barrier Disruption Consortium meeting.
The blood-brain barrier (BBB) presents a major obstacle to the treatment of malignant brain tumors and other central nervous… 
2005
2005
Synthesis, Expression and Purification of a Type of Chlorotoxin-like Peptide from the Scorpion, Buthus martensii Karsch, and its Acute Toxicity Analysis
A gene, rBmK Cta, encoding a chlorotoxin-like peptide from the scorpion, Buthus martensii Karsch, was synthesized according to… 
Highly Cited
2004
Highly Cited
2004
Radiation dosimetry of 131I-chlorotoxin for targeted radiotherapy in glioma-bearing mice
Chlorotoxin, or TM-601, is a peptide derived from the venom of the scorpionLeiurus Quinquestriatus that specifically binds to… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)