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Chlorotoxin

Known as: CTX 
A neurotoxin with potential anticancer property. Chlorotoxin (CTX) is a 36-amino acid peptide found in the venom of the deathstalker scorpion, and a… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

131-I-TM-601TM-601
CyclophosphamideNCIt Antineoplastic Agent Terminology

Broader (1)

Scorpion Venoms

Papers overview

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Review
2015
Review
2015
Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion
Chlorotoxin is a small 36 amino-acid peptide identified from the venom of the scorpion Leiurus quinquestriatus. Initially… 
Highly Cited
2010
Highly Cited
2010
Chlorotoxin labeled magnetic nanovectors for targeted gene delivery to glioma.
Glioma accounts for 80% of brain tumors and currently remains one of the most lethal forms of cancers. Gene therapy could… 
Highly Cited
2008
Highly Cited
2008
In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes.
Converging advances in the development of nanoparticle-based imaging probes and improved understanding of the molecular biology… 
Highly Cited
2008
Highly Cited
2008
Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparticles.
AIMS This study examines the capabilities of an actively targeting superparamagnetic nanoparticle to specifically deliver… 
Highly Cited
2008
Highly Cited
2008
Dendrimer‐Functionalized Shell‐crosslinked Iron Oxide Nanoparticles for In‐Vivo Magnetic Resonance Imaging of Tumors
Non-invasive diagnosis and detection of early-stage tumorsis regarded as one of the current challenges in the biomedicalsciences… 
Review
2007
Review
2007
Targeted delivery of antitumoral therapy to glioma and other malignancies with synthetic chlorotoxin (TM-601)
Targeted therapies for cancer is a rapidly advancing field, but the identification of tumor-specific ligands has proven difficult… 
Highly Cited
2007
Highly Cited
2007
Dendrimer‐Functionalized Iron Oxide Nanoparticles for Specific Targeting and Imaging of Cancer Cells
We demonstrated a unique approach that combines a layer‐by‐layer (LbL) self‐assembly method with dendrimer chemistry to… 
Highly Cited
2005
Highly Cited
2005
Optical and MRI multifunctional nanoprobe for targeting gliomas.
A multifunctional nanoprobe capable of targeting glioma cells, detectable by both magnetic resonance imaging and fluorescence… 
Review
2002
Review
2002
An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch.
Highly Cited
1993
Highly Cited
1993
Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion.
We have previously demonstrated that the venom of the scorpion Leiurus quinquestriatus blocks small-conductance Cl- channels… 
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