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131-I-TM-601

Known as: I 131 TM-601, 131I-TM601, Iodine I 131 TM-601 
An iodine 131 (I 131) radioconjugate of the synthetic chlorotoxin (CTX) TM-601 with potential antiangiogenic and antineoplastic activities. CTX is a… 
National Institutes of Health

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Broader (2)

Chlorotoxiniodine I 131 chlorotoxin

Papers overview

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2016
2016
A phase I evaluation of intravenous TM601 in recurrent glioblastoma: Use of perfusion MRI to monitor antiangiogenic effects.
2041 Background: TM601, a synthetic chlorotoxin, is a peptide derived from scorpion venom. In vitro data demonstrate binding to… 
2011
2011
131I-TM-601 SPECT imaging of Human Glioma
Primary malignant brain tumors (gliomas) typically infiltrate deeply into surrounding normal brain tissue. Currently available… 
2009
2009
Dosimetry study of a phase II multiple-dose intracavitary administration of 131I-TM601 in adult patients with recurrent high-grade glioma.
e13006 Background: Postoperative radiotherapy for glioma has been shown to improve survival with increased radiation doses. Dose… 
2002
2002
TransMolecular receives FDA approval for 131-I-TM-601 IND application.
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