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Chimerin 1

Known as: Chimaerin, alpha-1, CHN1, alpha Chimaerin 
A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal… 
National Institutes of Health

Related topics

Related topics

16 relations
CHN1 geneCytoplasmic matrixDAG/PE-Binding DomainIn Blood

Broader (1)

GTPase-Activating Proteins

Papers overview

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Highly Cited
2007
Highly Cited
2007
Rac-GAP α-Chimerin Regulates Motor-Circuit Formation as a Key Mediator of EphrinB3/EphA4 Forward Signaling
Highly Cited
1996
Highly Cited
1996
The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia
n-Chimaerin is a GTPase-activating protein (GAP) mainly for Rac1 and less so for Cdc42Hs in vitro. The GAP activity of n… 
Highly Cited
1993
Highly Cited
1993
A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42
THE Ras-related Rho subfamily of GTP-binding proteins (p21s), which includes Rho, Rac and Cdc42Hs, is implicated in different… 
Highly Cited
1993
Highly Cited
1993
A novel functional target for tumor-promoting phorbol esters and lysophosphatidic acid. The p21rac-GTPase activating protein n-chimaerin.
Highly Cited
1993
Highly Cited
1993
Germ cell beta-chimaerin, a new GTPase-activating protein for p21rac, is specifically expressed during the acrosomal assembly stage in rat testis.
Highly Cited
1992
Highly Cited
1992
Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signaling pathway from ras to the nucleus
Highly Cited
1992
Highly Cited
1992
Association between GTPase activators for Rho and Ras families
THE ras-related low-molecular-mass GTPases participate in signal transduction involving a variety of cellular functions… 
Highly Cited
1991
Highly Cited
1991
Bcr encodes a GTPase-activating protein for p21rac
MORE than thirty small guanine nucleotide-binding proteins related to the ras-encoded oncoprotein, termed Ras or p21ras, are… 
Highly Cited
1990
Highly Cited
1990
Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene.
Highly Cited
1990
Highly Cited
1990
Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor.
A human brain-specific cDNA encoding n-chimaerin, a protein of predicted molecular mass 34 kDa, has sequence identity with two… 
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