Chenodeoxycholate
National Institutes of Health
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We have demonstrated in vitro the efficacy of the taurine-conjugated dihydroxy bile salts deoxycholate and chenodeoxycholate in…
The in vivo formation of the sulfate ester of glycolithocholate is a critical step in the elimination of this hepatotoxic bile…
The association between reported intestinal fluid secretory activity of bile acids and Ca2+ ionophore properties was investigated…
A purification scheme is described for the neutral glutathione S-transferases of rat liver. Discontinuous sodium dodecyl sulphate…
The administration of chenodeoxycholate to most species results in hepatic lesions presumed to be due to lithocholate formed from…
Fasting concentrations of S-cholate, S-chenodeoxycholate, S-aminotransferases, S-bilirubin, S-alkaline phosphatases, and S…
Rapid, sensitive radioimmunoassays have been developed for the conjugated primary bile salts, cholate and chenodeoxycholate…
The concentration of individual bile acids in serum was measured in 18 neonates and infants with various cholestatic conditions…
Renal cortex, anterior uvea, lateral choroid plexus and terminal ileum accumulate -14C-cholate, glycocholate, deoxycholate and…
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The rate limiting enzyme of cholesterol biosynthesis, 3-hydroxy-3-methylglutaryl coenzyme A reductase, is found in the…