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Chemical Probe

Known as: Probe 
A small molecule that reacts with a known target in a predictable way, thereby showing location, identification, physiological state, etc.
National Institutes of Health

Papers overview

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2015
2015
HIF-1α suppressing small molecule, LW6, inhibits cancer cell growth by binding to calcineurin b homologous protein 1.
2013
2013
Chromogenic chemical probe for protein structural characterization via ultraviolet photodissociation mass spectrometry.
A chemical probe/ultraviolet photodissociation (UVPD) mass spectrometry strategy for evaluating structures of proteins and… 
Highly Cited
2012
Highly Cited
2012
Neural stem cell specific fluorescent chemical probe binding to FABP7
Fluorescent small molecules have become indispensable tools for biomedical research along with the rapidly developing optical… 
2010
2010
O(3P) atoms as a chemical probe of surface ordering in ionic liquids.
The reactivity of photolytically generated, gas-phase, ground-state atomic oxygen, O((3)P), with the surfaces of a series of 1… 
2006
2006
A new chemical probe for the detection of the cancer-linked galectin-3.
A chemical probe was developed for the detection of the emerging cancer marker galectin-3. The probe contains a benzophenone… 
Highly Cited
2005
Highly Cited
2005
Development of a Novel Chemical Probe for the Selective Enrichment of Phosphorylated Serine‐ and Threonine‐Containing Peptides
Gaining insight into phosphoproteomes is of the utmost importance for understanding regulation processes such as signal… 
1996
1996
Cluster-surface impact dissociation of halogen molecules in large inert gas clusters
1992
1992
Metal ions cause the isomerization of certain intramolecular triplexes.
Highly Cited
1986
Highly Cited
1986
Diethyl pyrocarbonate: a chemical probe for DNA cruciforms.
Two palindromic DNA sequences were analyzed with respect to their chemical reactivities with diethyl pyrocarbonate. In negatively… 
1968
1968
Molecular aspects of hydrogen-deuterium exchange in macromolecules.
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