Neural stem cell specific fluorescent chemical probe binding to FABP7.

  title={Neural stem cell specific fluorescent chemical probe binding to FABP7.},
  author={Seong-Wook Yun and Cheryl Leong and Duanting Zhai and Yee Ling Tan and Linda Lim and Xuezhi Bi and J Lee and Han Jo Kim and Nam-young Kang and Shin Hui Ng and Lawrence Walter Stanton and Y. -S. Chang},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={109 26},
Fluorescent small molecules have become indispensable tools for biomedical research along with the rapidly developing optical imaging technology. We report here a neural stem cell specific boron-dipyrromethane (BODIPY) derivative compound of designation red 3 (CDr3), developed through a high throughput/content screening of in-house generated diversity oriented fluorescence library in stem cells at different developmental stages. This novel compound specifically detects living neural stem cells… CONTINUE READING
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