Chaperonin Containing TCP-1

Known as: Cytosolic Chaperonin, Cytosolic Molecular Chaperone CCT, Chaperonin, Cytosolic 
A group II chaperonin found in eukaryotic CYTOSOL. It is comprised of eight subunits with each subunit encoded by a separate gene. This chaperonin is… (More)
National Institutes of Health

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Topic mentions per year

1971-2018
010203019712018

Papers overview

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Highly Cited
2008
Highly Cited
2008
The eukaryotic cytosolic chaperonin containing TCP-1 (CCT) has an important function in maintaining cellular homoeostasis by… (More)
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Highly Cited
2006
Highly Cited
2006
Polyglutamine (polyQ)-expansion proteins cause neurodegenerative disorders including Huntington's disease, Kennedy's disease and… (More)
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2005
2005
The eukaryotic cytoplasmic chaperonin containing TCP-1 (CCT) is a hetero-oligomeric complex that assists the folding of actins… (More)
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2003
2003
The chaperonin CCT (chaperonin containing t-complex polypeptide 1 (TCP-1)) from bovine testis was mixed rapidly with different… (More)
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2001
2001
Initial rates of ATP hydrolysis by the chaperonin containing TCP-1 (CCT) from bovine testis were measured as a function of ATP… (More)
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Highly Cited
1998
Highly Cited
1998
We describe the discovery of a heterohexameric chaperone protein, prefoldin, based on its ability to capture unfolded actin… (More)
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Highly Cited
1998
Highly Cited
1998
We have determined to 2.6 A resolution the crystal structure of the thermosome, the archaeal group II chaperonin from T… (More)
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1997
1997
We have cloned a novel Tcp-1-related mouse testis cDNA encoding a polypeptide of 531 amino acids which shares 81.2% identity with… (More)
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1995
1995
The chaperonin containing t-complex polypeptide 1 (TCP-1), as one of its subunits, CCT, is a cytosolic heterooligomeric molecular… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND TCP-1 is a 60 kD subunit of a cytosolic hetero-oligomeric chaperone that is known to be involved in the folding of… (More)
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