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Centroblast

Known as: Large Non-Cleaved Follicle Center Cell 
An activated B-lymphocyte found in the germinal centers. It has a large nucleus without clefts, finely dispersed chromatin, and a rim of basophilic… 
National Institutes of Health

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Hematopoietic and Lymphoid TissueLymphoid TissuePlasma CellsStructure of germinal center of lymph node

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Mitotic Index Determined by Phosphohistone H3 Immunohistochemistry for Precise Grading in Follicular Lymphoma
The World Health Organization classification recommends follicular lymphoma (FL) grading (G1-3) by considering centroblast number… 
2010
2010
c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma
The germinal center (GC) reaction has a pivotal function in human B-cell lymphomagenesis. Genetic aberrations occurring during… 
Review
2008
Review
2008
Morphologic, immunphenotypic and clinical discriminators between T-cell/histiocyte-rich large B-cell lymphoma and lymphocyte-predominant Hodgkin lymphoma.
2008
2008
Large B-cell transformation of chronic lymphocytic leukemia presenting as a penile mass and skin lesion.
Review
2004
Review
2004
Somatic hypermutation: a mutational panacea.
2003
2003
Naive and memory B cells respond differentially to T‐dependent signaling but display an equal potential for differentiation toward the centroblast‐restricted CD77/globotriaosylceramide phenotype
Resting (CD38low) tonsillar B cells differentiate to express the centroblast‐restricted CD77/globotriaosylceramide antigen on… 
2001
2001
Does recycling in germinal centres exist?
A general criterion is formulated to decide if the recycling of B cells exists in germinal centre (GC) reactions. The criterion… 
1997
1997
Terminal differentiation of human germinal center B cells in vitro.
In order to define an in vitro culture system allowing growth of single human germinal center B cells (GC-B), we have studied the… 
1995
1995
T‐cell‐rich B‐cell lymphoma and lymphocyte‐predominant Hodgkin's disease: two closely related entities?
Summary. T‐cell‐rich B‐cell lymphoma (TCRBCL) is a recently described variant of non‐Hodgkin's lymphoma. It may arise de novo or… 
1988
1988
Prognostic indicators in centroblastic-centrocytic lymphoma.
The prognostic importance of ploidy and proliferative index (%S + G2) assessed by flow cytometry, mitotic and centroblast counts… 
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