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Centroblast

Known as: Large Non-Cleaved Follicle Center Cell 
An activated B-lymphocyte found in the germinal centers. It has a large nucleus without clefts, finely dispersed chromatin, and a rim of basophilic… 
National Institutes of Health

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Hematopoietic and Lymphoid TissueLymphoid TissuePlasma CellsStructure of germinal center of lymph node

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma
The germinal center (GC) reaction has a pivotal function in human B-cell lymphomagenesis. Genetic aberrations occurring during… 
Review
2008
Review
2008
Morphologic, immunphenotypic and clinical discriminators between T-cell/histiocyte-rich large B-cell lymphoma and lymphocyte-predominant Hodgkin lymphoma.
2006
2006
Inactivation of the PRDM 1 / BLIMP 1 gene in diff use large B cell lymphoma
JEM © The Rockefeller University Press $8.00 Vol. 203, No. 2, February 20, 2006 311–317 www.jem.org/cgi/doi/10.1084/jem.20052204… 
2003
2003
Naive and memory B cells respond differentially to T‐dependent signaling but display an equal potential for differentiation toward the centroblast‐restricted CD77/globotriaosylceramide phenotype
Resting (CD38low) tonsillar B cells differentiate to express the centroblast‐restricted CD77/globotriaosylceramide antigen on… 
Highly Cited
2002
Highly Cited
2002
An unusual Fc receptor-related protein expressed in human centroblasts
Here, we report the identification of Fc receptor homolog expressed in B cells (FREB), a unique B cell-specific molecule that is… 
2001
2001
Does recycling in germinal centres exist?
A general criterion is formulated to decide if the recycling of B cells exists in germinal centre (GC) reactions. The criterion… 
2000
2000
A new in vivo and in vitro B cell lymphoma model, pi-BCL1.
We report a new variant of the BCL1 syngeneic mouse B-cell lymphoma model, which we have called pi-BCL1. pi-BCL1 can be… 
1997
1997
Terminal differentiation of human germinal center B cells in vitro.
In order to define an in vitro culture system allowing growth of single human germinal center B cells (GC-B), we have studied the… 
1995
1995
T‐cell‐rich B‐cell lymphoma and lymphocyte‐predominant Hodgkin's disease: two closely related entities?
Summary. T‐cell‐rich B‐cell lymphoma (TCRBCL) is a recently described variant of non‐Hodgkin's lymphoma. It may arise de novo or… 
1988
1988
Prognostic indicators in centroblastic-centrocytic lymphoma.
The prognostic importance of ploidy and proliferative index (%S + G2) assessed by flow cytometry, mitotic and centroblast counts… 
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