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Centenarians

Known as: 100+ years old, Centenarian, centenarian human (100+) 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BackgroundIt has been reported that the composition of human gut microbiota changes with age; however, few studies have used… Expand
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Highly Cited
2012
Highly Cited
2012
Human aging cannot be fully understood in terms of the constrained genetic setting. Epigenetic drift is an alternative means of… Expand
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Highly Cited
2010
Highly Cited
2010
Background Age-related physiological changes in the gastrointestinal tract, as well as modifications in lifestyle, nutritional… Expand
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Highly Cited
2009
Highly Cited
2009
The human forkhead box O3A gene (FOXO3A) encodes an evolutionarily conserved key regulator of the insulin–IGF1 signaling pathway… Expand
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Review
2009
Review
2009
If the pace of increase in life expectancy in developed countries over the past two centuries continues through the 21st century… Expand
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Highly Cited
2008
Highly Cited
2008
Rather than being a passive, haphazard process of wear and tear, lifespan can be modulated actively by components of the insulin… Expand
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Review
2003
Review
2003
Restriction of the number of calories consumed extends longevity in many organisms. In rodents, caloric restriction decreases the… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The compression of morbidity hypothesis predicts that, in order to achieve their extreme old age, centenarians… Expand
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Review
2000
Review
2000
In this paper we extend the "network theory of aging," and we argue that a global reduction in the capacity to cope with a… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Inflammatory mechanisms and immune activation have been hypothesized to play a role in the pathogenesis of age… Expand
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