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Background In a phase 1 trial, axicabtagene ciloleucel (axi‐cel), an autologous anti‐CD19 chimeric antigen receptor (CAR) T‐cell… Expand CD19 CAR T cell therapy induces complete remissions in 88% of 16 adult patients with relapsed or refractory acute lymphoblastic… Expand BACKGROUND
Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies… Expand BACKGROUND
Cellular therapies could play a role in cancer treatment and regenerative medicine if it were possible to quickly… Expand Heart failure is the leading cause of death worldwide, and current therapies only delay progression of the disease. Laboratory… Expand Animal and preliminary human studies of adult cell therapy following acute myocardial infarction have shown an overall… Expand PURPOSE
The two approved treatments for patients with metastatic melanoma, interleukin (IL)-2 and dacarbazine, mediate objective… Expand Stem cells represent natural units of embryonic development and tissue regeneration. Embryonic stem (ES) cells, in particular… Expand Treatment with isolated allogeneic mesenchymal cells has the potential to enhance the therapeutic effects of conventional bone… Expand Myeloablative conditioning associated with hazardous immediate and late complications is considered as a mandatory first step in… Expand