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Cathepsin G

Known as: Cathepsin G [Chemical/Ingredient] 
A serine protease found in the azurophil granules of NEUTROPHILS. It has an enzyme specificity similar to that of chymotrypsin C.
National Institutes of Health

Related topics

Related topics

12 relations
CTSG geneCathepsin G Ab:PrThr:Pt:Ser:OrdIn BloodProcess of secretion

Narrower (1)

CTSG protein, human

Broader (2)

Serine EndopeptidasesSerine Proteases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Consequences of cathepsin C inactivation on membrane expression of proteinase 3 , the target antigen in autoimmune vasculitis
Membrane-bound proteinase 3 (PR3) is the main target antigen of anti-neutrophil cytoplasmic autoantibodies (ANCA) in… 
2013
2013
Targeting cathepsin G in myeloid leukemia
Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the… 
2012
2012
Cathepsin G Induces Cell Aggregation of Human Breast Cancer MCF-7 Cells via a 2-Step Mechanism: Catalytic Site-Independent Binding to the Cell Surface and Enzymatic Activity-Dependent Induction of…
Neutrophils often invade various tumor tissues and affect tumor progression and metastasis. Cathepsin G (CG) is a serine protease… 
2009
2009
S1649 Intracolonic Infusion of Fecal Supernatant from UC Patients Triggers Altered Permeability and Inflammation in Mice: Role of Cathepsin G and Protease-Activated Receptor-4
2009
2009
Sensor materials for the detection of proteases.
Review
2002
Review
2002
Tailoring an antibacterial peptide of human lysosomal cathepsin G to enhance its broad-spectrum action against antibiotic-resistant bacterial pathogens.
Neutrophils contain several cationic antimicrobial proteins or peptides (CAPs) that exert antibiotic-like action against bacteria… 
2001
2001
Characterization of Polymorphic Structure of Cathepsin G Gene: Role in Cardiovascular and Cerebrovascular Diseases
Cathepsin G (CTSG), a serine protease released from activated neutrophils, may cause platelet activation, leading to… 
1994
1994
Inhibition of human neutrophil elastase and cathepsin G by a biphenyl disulfonic acid copolymer.
1992
1992
Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G.
A large series of variously substituted anthraquinones has been synthesized and assayed for inhibitory capacity against human… 
1992
1992
Heparin inhibits neutrophil-induced platelet activation via cathepsin G.
Activated human polymorphonuclear neutrophils (PMNs) induce platelet stimulation via cathepsin G (cat G), a platelet-activating… 
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