Casodex

Known as: AstraZeneca brand of bicalutamide, Zeneca brand of bicalutamide, Astra brand of bicalutamide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
05101519892017

Papers overview

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2007
2007
Prostate tumors are initially dependent on androgens for growth, but the majority of patients treated with anti-androgen therapy… (More)
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2002
2002
The cellular mechanisms of anti-androgen-induced tumor regression have not been investigated in great detail. We have compared… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVES To evaluate the efficacy and tolerability of 'Casodex' monotherapy (150 mg daily) for metastatic and locally advanced… (More)
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Highly Cited
1998
Highly Cited
1998
The molecular mechanism of androgen-independent growth of prostate cancer after androgen ablation was explored in LNCaP cells. An… (More)
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Highly Cited
1998
Highly Cited
1998
Interleukin-6 (IL-6) levels are frequently elevated in sera of patients with metastatic prostate cancer. IL-6 receptors are… (More)
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1996
1996
1. The biologic activity of androgens is mediated through the formation of a non-covalent androgen receptor (AR)-steroid complex… (More)
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1995
1995
Total androgen blockade with castration and antiandrogens has become the primary therapy in metastatic prostate carcinoma… (More)
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Highly Cited
1994
Highly Cited
1994
Aberrant activation of the androgen receptor (AR) may be one of the mechanisms which contribute to progression of prostatic… (More)
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1994
1994
OBJECTIVE To evaluate the relationship between antiandrogen withdrawal and change in prostate-specific antigen (PSA) when the… (More)
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1993
1993
1. Casodex, a non-steroidal antiandrogen, was eliminated primarily in faeces by rat, mouse, rabbit and dog. Rat, mouse and rabbit… (More)
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