Carfecillin

Known as: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((1,3-dioxo-3-phenoxy-2-phenylpropyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-, Carfecillin [Chemical/Ingredient], Carphecillin 
The phenyl ester of CARBENICILLIN that, upon oral administration, is broken down in the intestinal mucosa to the active antibacterial. It is used for… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-1994
012319741994

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Physical and technological parameters of carfecillin powder and carfecillin with auxiliary substances in the form of the powder… (More)
Is this relevant?
1981
1981
Two hundred patients undergoing prostatic surgery at 2 hospitals were randomly allocated into 4 equal groups. The groups were a… (More)
Is this relevant?
1980
1980
1. Studies have shown that hydrolysis of carfecillin to carbenicillin and phenol in vitro occurs in blood, liver and gut tissues… (More)
Is this relevant?
1980
1980
1. The absorption of the phenol moiety of [phenol-14C]carfecillin following oral administration to rat, dog and man was extensive… (More)
Is this relevant?
Review
1979
Review
1979
Following a review of the latest methods of treating infections of the urinary ways, the pharmacokinetic and clinical results of… (More)
Is this relevant?
1978
1978
The pharmacokinetics of carfecillin (Carbenicillin-phenyl-ester) were studied in 10 healthy subjects, in 5 patients with hepatic… (More)
Is this relevant?
1978
1978
Acute toxicity of oral and intraperitoneal carfecillin was studied on different species of laboratory animals, such as albino… (More)
Is this relevant?
1977
1977
The pharmacokinetics of carfecillin and carindacillin was compared in 10 volunteers. The pharmacokinetic parameters of both… (More)
Is this relevant?
1977
1977
Carfecillin, the alpha-phenyl ester of carbenicillin, hydrolyses rapidly in the presence of serum or body tissues to liberate… (More)
Is this relevant?
1975
1975
A patient with Goodpasture's syndrome has recovered after treatment with immunosuppressive drugs (cyclophosphamide and… (More)
Is this relevant?