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Carfecillin

Known as: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((1,3-dioxo-3-phenoxy-2-phenylpropyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-, Carfecillin [Chemical/Ingredient], Carphecillin 
The phenyl ester of CARBENICILLIN that, upon oral administration, is broken down in the intestinal mucosa to the active antibacterial. It is used for… Expand
National Institutes of Health

Papers overview

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1991
1991
Sixty-three drugs, belonging to 10 chemical classes, were tested in vitro to determine effects on phagocytosis of 32P-labeled… Expand
1984
1984
The aggregation of a number of penicillins, both in water and in electrolyte solution, has been examined by total intensity light… Expand
1984
1984
The minimal inhibitory concentrations (MIC) of carbenicillin, ticarcillin and BL-P 1654 for gram-negative udder pathogens were… Expand
1981
1981
Two hundred patients undergoing prostatic surgery at 2 hospitals were randomly allocated into 4 equal groups. The groups were a… Expand
1980
1980
1. Studies have shown that hydrolysis of carfecillin to carbenicillin and phenol in vitro occurs in blood, liver and gut tissues… Expand
1980
1980
1. The absorption of the phenol moiety of [phenol-14C]carfecillin following oral administration to rat, dog and man was extensive… Expand
1977
1977
The pharmacokinetics of carfecillin and carindacillin was compared in 10 volunteers. The pharmacokinetic parameters of both… Expand
1977
1977
Carfecillin, the alpha-phenyl ester of carbenicillin, hydrolyses rapidly in the presence of serum or body tissues to liberate… Expand
1975
1975
Blood and urine levels of carbenicillin were measured in 10 healthy volunteers and four patients with renal failure after single… Expand
1975
1975
Twelve alpha-carboxy esters of carbenicillin, a parenteral broad spectrum semisynthetic penicillin, were synthesized and examined… Expand