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Cardiotoxicity

Known as: Cardiac Toxicities, Toxicity, Cardiac, Cardiac Toxicity 
Toxicity that impairs or damages the heart. This condition is often caused by the administration of a pharmaceutical agent that initiates a poisonous… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Doxorubicin is believed to cause dose-dependent cardiotoxicity through redox cycling and the generation of reactive oxygen… Expand
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Review
2007
Review
2007
BACKGROUND Sunitinib, a multitargeted tyrosine-kinase inhibitor, which is approved by both US and European Commission regulatory… Expand
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Review
2007
Review
2007
Cancer therapy has progressed remarkably in recent years. In no area has this been more apparent than in the development of… Expand
Highly Cited
2007
Highly Cited
2007
We assessed cardiovascular disease (CVD) incidence in 1474 survivors of Hodgkin lymphoma (HL) younger than 41 years at treatment… Expand
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Highly Cited
2006
Highly Cited
2006
Imatinib mesylate (Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous… Expand
Review
2004
Review
2004
The clinical use of anthracyclines like doxorubicin and daunorubicin can be viewed as a sort of double-edged sword. On the one… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… Expand
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Review
1990
Review
1990
Anthracyclines, such as doxorubicin and daunorubicin, are highly effective anticancer agents that produce a well‐described but… Expand
Highly Cited
1982
Highly Cited
1982
Doxorubicin (Adriamycin) was administered by continuous infusion to reduce peak plasma levels and thus lessen cardiac toxicity… Expand
Highly Cited
1973
Highly Cited
1973
The cardiotoxic effects of adriamycin were studied in 399 patients treated for far‐advanced carcimma. Forty‐five patients (11… Expand