Carcinogenic Aromatic Amine
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Aromatic amines and heterocyclic aromatic amines (HAAs) are a class of structurally related carcinogens that are formed during… Expand Azo dyes represent the major class of dyestuffs. They are metabolised to the corresponding amines by liver enzymes and the… Expand Experimental studies involving the carcinogenic aromatic amine 2-(acetylamino)fluorene (AAF) have afforded two acetylated DNA… Expand Hepatocarcinogenic aromatic amines such as 4-aminoazobenzene derivatives and heterocyclic aromatic amines of cooked food origin… Expand The N-hydroxyl and/or N-acetoxy derivatives of carcinogenic 4-aminoazo dyes, which were thought to be proximate and ultimate… Expand 2,4-Diaminotoluene (2,4-DAT) is a mutagenic and hepatocarcinogenic aromatic amine, requiring metabolic activation. We have found… Expand Rat liver microsomal enzyme(s) that catalyze mutagenic activation of a carcinogenic aminoazo dye, 3-methoxy-4-aminoazobenzene (3… Expand The oxidation of benzidine, a carcinogenic aromatic amine, by H2O2 is catalyzed by horseradish peroxidase or lactoperoxidase. The… Expand The carcinogenic aromatic amine 3,3'-dimethoxybenzidine (DMOB) was rapidly metabolized in the rat. Thirty minutes after iv… Expand