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Cap-Binding Protein Complex

Known as: Cap Binding Protein Complex 
A heterodimeric protein complex of RNA cap-binding proteins which binds with high affinity to the 5' MRNA CAP STRUCTURE.
National Institutes of Health

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Broader (1)

RNA Cap-Binding Proteins

Papers overview

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2002
2002
Cytoplasmic Expression of mRNAs Containing the Internal Ribosome Entry Site and 3′ Noncoding Region of Hepatitis C Virus: Effects of the 3′ Leader on mRNA Translation and mRNA Stability
ABSTRACT Translation initiation in many eukaryotic mRNAs is modulated by an interaction between the cap binding protein complex… 
Highly Cited
1991
Highly Cited
1991
The effect of poliovirus proteinase 2Apro expression on cellular metabolism. Inhibition of DNA replication, RNA polymerase II transcription, and translation.
Highly Cited
1990
Highly Cited
1990
Cap binding protein complex that restores protein synthesis in heat-shocked Ehrlich cell lysates contains highly phosphorylated eIF-4E.
Highly Cited
1990
Highly Cited
1990
Association of initiation factor eIF-4E in a cap binding protein complex (eIF-4F) is critical for and enhances phosphorylation by protein kinase C.
1989
1989
Secondary structure analysis of adenovirus tripartite leader.
1985
1985
Poliovirus protease does not mediate cleavage of the 220,000-Da component of the cap binding protein complex.
Poliovirus infection of HeLa cells results in a rapid shutoff of host protein synthesis but does not inhibit the translation of… 
1985
1985
Poliovirus protease 3C (P3-7c) does not cleave P220 of the eucaryotic mRNA cap-binding protein complex
Infection of HeLa cells by poliovirus results in proteolysis of the large subunit (P220) of the cap-binding protein complex. This… 
Highly Cited
1984
Highly Cited
1984
Functional characterization of eukaryotic mRNA cap binding protein complex: effects on translation of capped and naturally uncapped RNAs.
We examined the effects of a eukaryotic mRNA cap binding protein (CBP) complex purified by cap analogue affinity chromatography… 
Review
1983
Review
1983
Role of mRNA competition in regulating translation: further characterization of mRNA discriminatory initiation factors.
Host and reovirus mRNAs compete with one another for translation in infected cells. Kinetic analysis has suggested that the site… 
Highly Cited
1983
Highly Cited
1983
Involvement of eukaryotic initiation factor 4A in the cap recognition process.
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