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Candidate Gene Identification

Known as: Candidate Gene Association Studies, Gene Discovery, Identification, Candidate Gene 
The determination of genes suspected to be associated with specific traits, metabolic pathways, or diseases.
National Institutes of Health

Related topics

Related topics

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Broader (1)

Genetic Association Studies

Papers overview

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Highly Cited
2018
Highly Cited
2018
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1 million… Expand
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Review
2011
Review
2011
Exome sequencing as a tool for Mendelian disease gene discovery
Exome sequencing — the targeted sequencing of the subset of the human genome that is protein coding — is a powerful and cost… Expand
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Review
2010
Review
2010
Biosynthesis of glucosinolates--gene discovery and beyond.
Glucosinolates are sulfur-rich secondary metabolites characteristic of the Brassicales order with important biological and… Expand
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Highly Cited
2008
Highly Cited
2008
Disease candidate gene identification and prioritization using protein interaction networks
BackgroundAlthough most of the current disease candidate gene identification and prioritization methods depend on functional… Expand
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Review
2005
Review
2005
Drug therapy for acute myeloid leukemia.
Although improvement in outcomes has occurred in younger adults with acute myeloid leukemia (AML) during the past 4 decades… Expand
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Highly Cited
2003
Highly Cited
2003
Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action
Type 2 diabetes is an increasingly common, serious metabolic disorder with a substantial inherited component. It is characterised… Expand
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Highly Cited
2002
Highly Cited
2002
Combining mapping and arraying: An approach to candidate gene identification
A combination of quantitative trait locus (QTL) mapping and microarray analysis was developed and used to identify 34 candidate… Expand
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Highly Cited
2001
Highly Cited
2001
Immune gene discovery by expressed sequence tag analysis of hemocytes and hepatopancreas in the Pacific White Shrimp, Litopenaeus vannamei, and the Atlantic White Shrimp, L. setiferus.
A pilot program was undertaken in immune gene discovery in two sister species of litopenaeid shrimp, the Pacific white shrimp… Expand
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Highly Cited
2000
Highly Cited
2000
DNASTAR's Lasergene sequence analysis software.
  • T. Burland
  • Methods in molecular biology
  • 2000
    • Corpus ID: 20706891
Lasergene's eight modules provide tools that enable users to accomplish each step of sequence analysis, from trimming and… Expand
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Highly Cited
1998
Highly Cited
1998
Gene discovery in the wood-forming tissues of poplar: analysis of 5, 692 expressed sequence tags.
A rapidly growing area of genome research is the generation of expressed sequence tags (ESTs) in which large numbers of randomly… Expand
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