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Cadherin-2

Known as: Neural Cadherin, Neural-Cadherin, CD325 Antigen 
Cadherin-2 (906 aa, ~100 kDa) is encoded by the human CDH2 gene. This protein is involved in both neural stem cell anchorage and quiescence.
National Institutes of Health

Related topics

Related topics

12 relations
ADH-1CDH2 geneCadherin DomainCell Adhesion

Broader (1)

N-Cadherins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Impact of pH on the structure and function of neural cadherin.
Neural (N-) cadherin is a transmembrane protein within adherens junctions that mediates cell-cell adhesion. It has 5 modular… 
Highly Cited
2008
Highly Cited
2008
Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay.
Well-controlled studies of the structural and functional interactions between cardiomyocytes and other cells are essential for… 
2008
2008
Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney.
The cadherins are cell adhesion molecules required for cellular homeostasis, and N-cadherin is the predominant cadherin expressed… 
2006
2006
Axon behavior in the olfactory nerve reflects the involvement of catenin–cadherin mediated adhesion
The projection of olfactory sensory neuron (OSN) axons to the olfactory bulb (OB) is a complex but well‐regulated process… 
Review
2002
Review
2002
Regulated Binding of a PTP 1 B-like Phosphatase to N-Cadherin : Control of Cadherin-mediated Adhesion by Dephosphorylation of-Catenin
Cadherins are a family of cell-cell adhesion molecules which play a central role in controlling morphogenetic movements during… 
Highly Cited
2001
Highly Cited
2001
Identification of an N-cadherin Motif That Can Interact with the Fibroblast Growth Factor Receptor and Is Required for Axonal Growth*
In this study, we show that the neurite outgrowth response stimulated by N-cadherin is inhibited by a recently developed and… 
Highly Cited
2001
Highly Cited
2001
Protease-active extracellular protein preparations from Porphyromonas gingivalis W83 induce N-cadherin proteolysis, loss of cell adhesion, and apoptosis in human epithelial cells.
BACKGROUND The protease-induced cytotoxicity of P. gingivalis may partly result from alteration of the extracellular matrix and… 
Highly Cited
1996
Highly Cited
1996
N-cadherin expression and function in cultured oligodendrocytes.
1996
1996
Ventral neural cadherin, a novel cadherin expressed in a subset of neural tissues in the zebrafish embryo
Cadherins are calcium‐binding transmembrane glycoproteins that are important mediators of cell‐cell association. Here we describe… 
Highly Cited
1992
Highly Cited
1992
Evidence for endogenous proteases, mRNA level and insulin as multiple mechanisms of N-cadherin down-regulation during retinal development.
Our previous studies of the role of cell adhesion in retinal development have focused on the expression and function of N… 
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