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CYR61 wt Allele

Known as: CCN1, Cysteine-Rich Protein 61, Mouse, Homolog of Gene, CCN Family, Member 1 Gene 
Human CYR61 wild-type allele is located in the vicinity of 1p22.3 and is approximately 3 kb in length. This allele, which encodes protein CYR61, is… 
National Institutes of Health

Related topics

Related topics

7 relations
Angiogenic ProcessApoptosisCell AdhesionCell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
CCN1 Promotes VEGF Production in Osteoblasts and Induces Endothelial Progenitor Cell Angiogenesis by Inhibiting miR‐126 Expression in Rheumatoid Arthritis
Angiogenesis is the formation of new capillaries from preexisting vasculature. The perpetuation of angiogenesis plays a critical… 
2015
2015
CCN1 Secreted by Tonsil‐Derived Mesenchymal Stem Cells Promotes Endothelial Cell Angiogenesis via Integrin αvβ3 and AMPK
CCN1 is highly expressed in cancer cells and has been identified in the secretome of bone marrow‐derived mesenchymal stem cells… 
2014
2014
CCN1 enables Fas ligand-induced apoptosis in cardiomyoblast H9c2 cells by disrupting caspase inhibitor XIAP.
2013
2013
Extracellular matrix protein CCN1 regulates cardiomyocyte apoptosis in mice with stress-induced cardiac injury.
AIMS Expression of extracellular matrix protein CCN1 is induced in end-stage ischaemic cardiomyopathy in humans, and after… 
2011
2011
The Matricellular Protein Cysteine-rich Protein 61 (CCN1/Cyr61) Enhances Physiological Adaptation of Retinal Vessels and Reduces Pathological Neovascularization Associated with Ischemic Retinopathy*
Retinal vascular damages are the cardinal hallmarks of retinopathy of prematurity (ROP), a leading cause of vision impairment and… 
2009
2009
Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3—modulated adhesion and invasion
Chaperone protein quantity may regulate the balance of proteins involved in invasion and malignancy. BAG3 is a co‐chaperone and… 
Highly Cited
2007
Highly Cited
2007
The angiogenic factor CCN1 promotes adhesion and migration of circulating CD34+ progenitor cells: potential role in angiogenesis and endothelial regeneration.
Tissue regeneration involves the formation of new blood vessels regulated by angiogenic factors. We reported recently that the… 
2007
2007
Expression of CCN1 (CYR61) in developing, normal, and diseased human kidney.
CCN1 (cysteine-rich protein 61; Cyr61) is an extracellular matrix-associated signaling molecule that functions in cell migration… 
2007
2007
CCN1 protects cardiac myocytes from oxidative stress via beta1 integrin-Akt pathway.
Highly Cited
2003
Highly Cited
2003
Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61).
The angiogenic inducer CCN1 (cysteine-rich 61, CYR61), a secreted matricellular protein of the CCN family, is a ligand of… 
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