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CYP4B1 gene

Known as: CYP4B1, CYTOCHROME P450, SUBFAMILY IVB, MEMBER 1, cytochrome P450 family 4 subfamily B member 1 
National Institutes of Health

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cytochrome P-450 CYP4B1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies
Engineering autologous or allogeneic T cells to express a suicide gene can control potential toxicity in adoptive T-cell… 
Review
2011
Review
2011
Xenobiotic metabolism and disposition in human lung: transcript profiling in non-tumoral and tumoral tissues.
2006
2006
The cytochromes P450 (CYP) response to allergic inflammation of the lung.
2003
2003
Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group.
Highly Cited
2001
Highly Cited
2001
Detection of cytochrome P450 mRNA transcripts in prostate samples by RT‐PCR
Background The expression of cytochrome P450 (CYP)‐dependent mono‐oxygenases in the prostate is important, as it will determine… 
Highly Cited
2001
Highly Cited
2001
Covalent linkage of prosthetic heme to CYP4 family P450 enzymes.
An extensive body of research on the structural properties of cytochrome P450 enzymes has established that these proteins possess… 
2001
2001
A transgenic mouse expressing human CYP4B1 in the liver.
The human CYP4B1 protein was expressed in the liver of a transgenic mouse line under the control of the promoter of the human… 
2001
2001
Active site characteristics of CYP4B1 probed with aromatic ligands.
The active site topography of rabbit CYP4B1 has been studied relative to CYP2B1 and CYP102 using a variety of aromatic probe… 
1998
1998
A chimeric fusion protein of cytochrome CYP4B1 and green fluorescent protein for detection of pro-drug activating gene delivery and for gene therapy in malignant glioma.
Quantity and distribution of transgene-expressing tumor cells are central issues in cancer gene therapy. These are critical for… 
Highly Cited
1996
Highly Cited
1996
Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy.
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