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cytochrome P-450 CYP4B1

Known as: CYP4B1, CYPIVB1 
 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The present study compared the relative expression pattern of 10 orthologous CYP forms from families 1-4 in cDNA panels of human… Expand
Highly Cited
2004
Highly Cited
2004
Environmental chemicals are one of the risk factors in breast cancer genesis. Cytochrome P450 (CYP) enzymes play a major role in… Expand
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Highly Cited
2000
Highly Cited
2000
In experimental animals such as rats and rabbits, CYP4B1 has an important role in mutagenic activation of procarcinogens in… Expand
Review
1998
Review
1998
Practically all lipid-soluble xenobiotics enter the conceptus through placental transfer. Many xenobiotics, including a number of… Expand
Highly Cited
1998
Highly Cited
1998
Vector-mediated transfer of prodrug-activating genes provides a promising means of cancer gene therapy. In a search for more… Expand
Review
1997
Review
1997
In both animal models and humans, the first and obligatory step in the activation of arylamines is N-hydroxylation. This pathway… Expand
Highly Cited
1995
Highly Cited
1995
The cytochrome P450-dependent terminal desaturation of valproic acid (VPA) is of both toxicological and mechanistic interest… Expand
Highly Cited
1994
Highly Cited
1994
The rate of formation of styrene glycol from styrene was compared in human, rat, and mouse liver microsomes. At a low styrene… Expand
Highly Cited
1994
Highly Cited
1994
Cytochrome P450 (CYP) enzymes expressed in human lung can metabolize a variety of xenobiotics, drugs, and endogenous compounds… Expand
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Highly Cited
1991
Highly Cited
1991
4-Ipomeanol is a pulmonary toxin in cattle and rodents that is metabolically activated by cytochromes P-450 (P-450s). P-450… Expand
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