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cytochrome P-450 CYP4B1

Known as: CYP4B1, CYPIVB1 
 
National Institutes of Health

Papers overview

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2011
2011
Genetic polymorphisms of enzymes involved in the metabolism of carcinogens are suggested to modify an individual's susceptibility… Expand
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Review
2006
Review
2006
CYP4B1 belongs to the mammalian CYP4 enzyme family that also includes CYP4A, 4F, 4V, 4X, and 4Z subfamilies. CYP4B1 shares with… Expand
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Highly Cited
2005
Highly Cited
2005
The present study compared the relative expression pattern of 10 orthologous CYP forms from families 1-4 in cDNA panels of human… Expand
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Highly Cited
2001
Highly Cited
2001
Environmental chemicals are one of the risk factors in breast cancer genesis. Cytochrome P450 (CYP) enzymes play a major role in… Expand
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2000
2000
In experimental animals such as rats and rabbits, CYP4B1 has an important role in mutagenic activation of procarcinogens in… Expand
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Review
1998
Review
1998
Practically all lipid-soluble xenobiotics enter the conceptus through placental transfer. Many xenobiotics, including a number of… Expand
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1998
1998
Long-term tamoxifen therapy is associated with increased risk of uterine endometrial cancer and benign alterations. Tamoxifen is… Expand
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1998
1998
Vector-mediated transfer of prodrug-activating genes provides a promising means of cancer gene therapy. In a search for more… Expand
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1994
1994
Cytochrome P450 (CYP) enzymes expressed in human lung can metabolize a variety of xenobiotics, drugs, and endogenous compounds… Expand
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1991
1991
4-Ipomeanol is a pulmonary toxin in cattle and rodents that is metabolically activated by cytochromes P-450 (P-450s). P-450… Expand
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