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CYP39A1 gene

Known as: Cytochrome P450, Family 39, Subfamily A, Polypeptide 1 Gene, CYTOCHROME P450, FAMILY 39, SUBFAMILY A, POLYPEPTIDE 1, CYP39A1 
This gene is involved in bile acid metabolism.
National Institutes of Health

Related topics

Related topics

8 relations
CYP39A1 protein, humanDigestionIron ChelationLipid Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Orphan Nuclear Receptor RORα Regulates Enzymatic Metabolism of Cerebral 24S-Hydroxycholesterol through CYP39A1 Intronic Response Element Activation
Oxysterols, important regulators of cholesterol homeostasis in the brain, are affected by neurodegenerative diseases. Early-onset… 
2019
2019
Ligand-binding properties and catalytic activity of the purified human 24-hydroxycholesterol 7α-hydroxylase, CYP39A1
2017
2017
Expression of oxysterol pathway genes in oestrogen‐positive breast carcinomas
This study investigated whether gene expression levels of key modulators of the oxysterol signalling pathway modify the prognosis… 
2016
2016
Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer
Oxysterols are oxidised derivatives of cholesterol, formed by the enzymatic activity of several cytochrome P450 enzymes and… 
2015
2015
Association of CYP39A1, RUNX2 and oxidized alpha-1 antitrypsin expression in relation to cholangiocarcinoma progression.
Cytochrome P450 (CYP) enzymes are a large family of constitutive and inducible mono-oxygenase enzymes that play a central role in… 
2015
2015
CYP39A1 polymorphism is associated with toxicity during intensive induction chemotherapy in patients with advanced head and neck cancer
Induction chemotherapy incorporating docetaxel, cisplatin and 5- fluorouracil before radiotherapy may improve the outcome of… 
2013
2013
Effect of genetic variants GSTA1 and CYP39A1 and age on busulfan clearance in pediatric patients undergoing hematopoietic stem cell transplantation.
BACKGROUND Busulfan is used in preparative regimens prior to stem cell transplantation in pediatric patients. There is… 
2012
2012
An SNP in CYP39A1 is associated with severe neutropenia induced by docetaxel
PurposeDocetaxel is one of the most widely used chemotherapy drugs for gynecological cancers. A dose-limiting factor of docetaxel… 
2009
2009
Identification of candidate epigenetic biomarkers for ovarian cancer detection.
Ovarian cancer ranks the most lethal among gynecologic neoplasms in women. To develop potential biomarkers for diagnosis, we have… 
2003
2003
Oxysterol 7α-Hydroxylase (CYP39A1) in the Ciliary Nonpigmented Epithelium of Bovine Eye
The CYP39A1 oxysterol 7α-hydroxylase preferentially catalyzes the 7α-hydroxylation of 24-hydroxycholesterol and has been… 
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