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CYP2D6*3 Allele

Known as: CYP2D6A, CYP2D6, g.2549delA, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*3 Allele 
Human CYP2D6*3 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
SummaryThe Far Eastern and Caucasian populations are strikingly different with respect to the debrisoquine/sparteine… 
1997
1997
Abstract The relationship between the cytochrome P450 (CYP) 2D6 genotype and the steady-state plasma concentrations (Css) of… 
Highly Cited
1996
Highly Cited
1996
Objective: Debrisoquine hydroxylase (CYP2D6) is responsible for the oxidative metabolism of many clinically used drugs. Since… 
1996
1996
The polymorphisms of debrisoquin (CYP2D6) and S-mephenytoin (CYP2C19) hydroxylation were studied in 210 unrelated healthy native… 
Highly Cited
1995
Highly Cited
1995
The CYP2D6 genotype and the debrisoquine and mephenytoin hydroxylation phenotypes were studied in 63 Oriental subjects including… 
1994
1994
Genotyping of five CYP2D6 alleles (wt, A,B,D,E) has been performed in 218 lung cancer patients and 289 healthy controls. PCR… 
1994
1994
The cytochrome P450 mono-oxygenases are a group of enzymes that metabolize a variety of exogenous and endogenous compounds, some… 
Highly Cited
1993
Highly Cited
1993
The objective of this study was to determine the CYP2D6 genotype of a black Zimbabwean population. Genotyping was carried out… 
Highly Cited
1993
Highly Cited
1993
Polymorphism of the gene encoding for debrisoquine hydroxylase, i.e. CYP2D6, was determined genotypically for 122 healthy… 
Highly Cited
1992
Highly Cited
1992
The molecular basis of polymorphic debrisoquin hydroxylation was studied in 223 Swedish white subjects, 187 extensive…