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CYP2D6*3 Allele

Known as: CYP2D6A, CYP2D6, g.2549delA, Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*3 Allele 
Human CYP2D6*3 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type… Expand
National Institutes of Health

Papers overview

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1998
1998
Four different loci have been found to be involved in the development of familial Alzheimer disease (AD). The epsilon4 allele of… Expand
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1997
1997
Abstract The relationship between the cytochrome P450 (CYP) 2D6 genotype and the steady-state plasma concentrations (Css) of… Expand
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Highly Cited
1996
Highly Cited
1996
Objective: Debrisoquine hydroxylase (CYP2D6) is responsible for the oxidative metabolism of many clinically used drugs. Since… Expand
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1996
1996
The polymorphisms of debrisoquin (CYP2D6) and S-mephenytoin (CYP2C19) hydroxylation were studied in 210 unrelated healthy native… Expand
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Highly Cited
1995
Highly Cited
1995
The CYP2D6 genotype and the debrisoquine and mephenytoin hydroxylation phenotypes were studied in 63 Oriental subjects including… Expand
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1994
1994
Genotyping of five CYP2D6 alleles (wt, A,B,D,E) has been performed in 218 lung cancer patients and 289 healthy controls. PCR… Expand
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Highly Cited
1993
Highly Cited
1993
The objective of this study was to determine the CYP2D6 genotype of a black Zimbabwean population. Genotyping was carried out… Expand
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1993
1993
Polymorphism of the gene encoding for debrisoquine hydroxylase, i.e. CYP2D6, was determined genotypically for 122 healthy… Expand
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Highly Cited
1992
Highly Cited
1992
The molecular basis of polymorphic debrisoquin hydroxylation was studied in 223 Swedish white subjects, 187 extensive… Expand
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Highly Cited
1991
Highly Cited
1991
SummaryThe Far Eastern and Caucasian populations are strikingly different with respect to the debrisoquine/sparteine… Expand
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