Deletion Mutation

Known as: Deletion Abnormality, Mutations, Deletion, Deletion Mutations 
Any rearrangement to the genomic content that results in the loss of one or more nucleotides of DNA. Deletions are generally irreversible… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1941-2018
020004000600019412017

Papers overview

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Review
2016
Review
2016
Single-strand annealing (SSA) is a DNA double-strand break (DSB) repair pathway that uses homologous repeats to bridge DSB ends… (More)
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Review
2016
Review
2016
Autophagy is a conserved multistep pathway that degrades and recycles damaged organelles and macromolecules to maintain… (More)
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Highly Cited
2006
Highly Cited
2006
Skeletal muscle-mass loss with age has severe health consequences, yet the molecular basis of the loss remains obscure. Although… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE In patients with non-small cell lung cancer (NSCLC), mutations in the epidermal growth factor receptor (EGFR) tyrosine… (More)
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Highly Cited
2002
Highly Cited
2002
The p53 tumour suppressor is activated by numerous stressors to induce apoptosis, cell cycle arrest, or senescence. To study the… (More)
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Highly Cited
2001
Highly Cited
2001
A subpopulation of collie dogs is extremely sensitive to neurotoxicity induced by ivermectin. The aim of this study was to… (More)
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Highly Cited
2001
Highly Cited
2001
A deletion of at least 140 kb starting approximately 35kb upstream (telomeric) to the GJB2 (CX26) gene was identified in 7… (More)
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Highly Cited
1996
Highly Cited
1996
Mouse Otx2 is a bicoid-class homeobox gene, related to the Drosophila orthodenticle (otd) gene. Expression of this gene is… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND The p53 tumor suppressor gene is mutated in a large percentage of human malignancies, including tumors of the colon… (More)
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Highly Cited
1989
Highly Cited
1989
About 60% of both Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) is due to deletions of the dystrophin… (More)
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