• Publications
  • Influence
MAP kinase signalling cascade in Arabidopsis innate immunity
TLDR
An Arabidopsis thaliana leaf cell system based on the induction of early-defence gene transcription by flagellin, a highly conserved component of bacterial flagella that functions as a PAMP in plants and mammals is developed, suggesting that signalling events initiated by diverse pathogens converge into a conserved MAPK cascade. Expand
Isochorismate synthase is required to synthesize salicylic acid for plant defence
TLDR
By cloning and characterizing an Arabidopsis defence-related gene (SID2) defined by mutation, it is shown that SA is synthesized from chorismate by means of ICS, and that SA made by this pathway is required for LAR and SAR responses. Expand
A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers.
TLDR
A set of mapping markers have been designed for Arabidopsis thaliana that correspond to DNA fragments amplified by the polymerase chain reaction (PCR) that can be unambiguously mapped to one of the 10Arabidopsis chromosome arms in a single cross using a limited number of F2 progeny. Expand
An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants.
TLDR
To facilitate genome-scale study of the opportunistic human pathogen Pseudomonas aeruginosa strain PA14, a nonredundant library of PA14 transposon mutants (the PA14NR Set) is constructed in which nonessential PA14 genes are represented by a singleTransposon insertion chosen from a comprehensive library of insertion mutants. Expand
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response
TLDR
It is shown that well-studied plant metabolites, previously identified as important in avoiding damage by herbivores, are also required as a component of the plant defense response against microbial pathogens. Expand
Common virulence factors for bacterial pathogenicity in plants and animals.
TLDR
A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model, indicating that these genes encode virulence factors required for the full expression of pathogenicity in both plants and animals. Expand
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
TLDR
It is proposed that virulence in this organism is both multifactorial and combinatorial, the result of a pool of pathogenicity-related genes that interact in various combinations in different genetic backgrounds. Expand
Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis.
TLDR
It is shown that a C. elegans pathogenicity model that is genetically tractable from the perspectives of both host and pathogen can be used to model mammalian bacterial pathogenesis. Expand
Signal transduction mutants of arabidopsis uncouple nuclear CAB and RBCS gene expression from chloroplast development
TLDR
This work has identified at least three Arabidopsis nuclear genes (GUN1, GUN2, and GUN3) necessary for coupling the expression of some nuclear genes to the functional state of the chloroplast and defines steps in one specific branch of a complex interorganellar regulatory network. Expand
...
1
2
3
4
5
...