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CYP2C9*3 Allele

Known as: CYP2C9, I359L, CYP2C9, c.1075A>C, Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*3 Allele 
Human CYP2C9*3 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele… Expand
National Institutes of Health

Papers overview

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2013
2013
Background and ObjectiveDespite the availability of several antiepileptic drugs, drug resistance remains one of the major… Expand
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2012
2012
  • H. Lee, M. Lim, +6 authors Y-R Yoon
  • Journal of clinical pharmacy and therapeutics
  • 2012
  • Corpus ID: 19550285
What is known and Objective:  Cytochrome P450 (CYP) 2C9 is a clinically important enzyme involved in the metabolism of many drugs… Expand
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2012
2012
The CYP2C9 enzyme metabolizes a wide range of relevant drugs, among which are oral anticoagulants. VKORC1 is the pharmacodynamic… Expand
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2005
2005
ObjectiveThere is considerable variability in the individual pharmaceutical dosages required to achieve optimal therapeutic… Expand
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Highly Cited
2004
Highly Cited
2004
Our objective was to identify genetic factors related to interindividual variability in the pharmacokinetics of ibuprofen and its… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractBackgroundApart from allergic mechanisms, a lack or mutation of metabolic enzymes may cause adverse drug reactions. Patch… Expand
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2004
2004
  • B. Yu, C. Luo, +5 authors H. Zhou
  • Clinica chimica acta; international journal of…
  • 2004
  • Corpus ID: 22068468
BACKGROUND Cytochromes P450 (CYP) 2C9 are polymorphic enzymes which catalyze a wide spectrum of drugs. It is also responsible for… Expand
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Highly Cited
2003
Highly Cited
2003
ObjectiveThis study analyzed the frequency of CYP2C9 variant alleles and evaluated the impact of CYP2C9 genotype on diclofenac… Expand
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Highly Cited
2002
Highly Cited
2002
Our objective was to investigate the effects of genetic polymorphisms of cytochrome P450 (CYP) 2C9 on the pharmacokinetics of… Expand
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Highly Cited
2001
Highly Cited
2001
Genetic polymorphisms were identified in the 5′‐flanking region of the human CYP2C9 gene, and their effects on the phenotype were… Expand
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