CYP2C9*2 Allele

Known as: CYP2C9*2, Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*2 Allele, CYP2C9, c.430C>T 
Human CYP2C9*2 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele… (More)
National Institutes of Health

Papers overview

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2013
2013
We previously documented the lowest frequency of CYP2C9*2 in Mexican indigenous Tepehuanos followed by Mestizos and Mexican… (More)
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2012
2012
The CYP2C9 enzyme metabolizes a wide range of relevant drugs, among which are oral anticoagulants. VKORC1 is the pharmacodynamic… (More)
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2011
2011
Earlier we had found that the CYP2C9*2 allelic frequency was lower in Mexican-Americans living in California than in Spaniards… (More)
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2011
2011
OBJECTIVE CYP2C9 is a major enzyme in human drug metabolism and the polymorphism observed in the corresponding gene may affect… (More)
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2010
2010
Dose requirements for oral anticoagulants in thromboembolic events are influenced by polymorphisms in VKORC1 and CYP2C9 genes… (More)
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2008
2008
OBJECTIVE Non-steroidal anti-inflammatory drugs (NSAID) induce gastroduodenal mucosal injury and are metabolized by cytochrome… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Chinese and Malay subjects have been reported to require less maintenance warfarin than Indians that could not be… (More)
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2005
2005
OBJECTIVE The goal of this study was to define the haplotype structure of the cytochrome P450 (CYP) 2C9 gene in a European… (More)
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Review
2003
Review
2003
INTRODUCTION A large (410-fold) interindividual variation in the dose requirement of warfarin to achieve optimal therapeutic… (More)
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Highly Cited
1999
Highly Cited
1999
Cytochrome P450 2C9 (CYP2C9) catalysis the metabolism of important drugs such as phenytoin, S-warfarin, tolbutamide, losartan… (More)
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