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CYP2C9*2 Allele

Known as: CYP2C9*2, Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*2 Allele, CYP2C9, c.430C>T 
Human CYP2C9*2 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele… 
National Institutes of Health

Related topics

Related topics

12 relations
10q24Cytosine to Thymidine Transition AbnormalityDecreased Biochemical ActivityIron Chelation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Do Genetic Contributors to Warfarin Responsiveness or Common Thrombophilias Influence the Risk of Major Bleeding in Patients on Extended Duration Vitamin K Antagonist (VKA) for Venous Thromboembolic…
Background: Recent studies have indicated that genetic factors such as polymorphisms in the CYP2C9 and the VKORC1 genes play an… 
2014
2014
Association of cytochrome P450 2C9 polymorphism with locally advanced head and neck squamous cell carcinoma and response to concurrent cisplatin-based radical chemoradiation
Abstract Aims: The aim of the present study is to investigate the association between polymorphism of cytochrome P450 2C9 (CYP2C9… 
2013
2013
Influence of admixture components on CYP2C9*2 allele frequency in eight indigenous populations from Northwest Mexico
We previously documented the lowest frequency of CYP2C9*2 in Mexican indigenous Tepehuanos followed by Mestizos and Mexican… 
2012
2012
Analysis of CYP2C9*2, CYP2C9*3 and VKORC1 -1639 G>A polymorphisms in a population from South-Eastern Europe
The CYP2C9 enzyme metabolizes a wide range of relevant drugs, among which are oral anticoagulants. VKORC1 is the pharmacodynamic… 
Review
2009
Review
2009
Warfarin pharmacogenomics.
Warfarin therapy is complicated by a narrow therapeutic index and substantial interpatient variability in dose response. The… 
Review
2008
Review
2008
Prevalence of CYP2C9 variants in the Mexican population.
2005
2005
Simultaneous genotyping of CYP2C9*2, *3, and 5′ flanking region (C-1189T) polymorphisms in a Spanish population through a new minisequencing multiplex single-base extension analysis
Objective. To conduct a descriptive study on the prevalence of relevant cytochrome P450 2C9 (CYP2C9) polymorphisms – the *2, *3… 
2004
2004
Frequency of Cytochrome P 450 2 C 9 ( CYP 2 C 9 ) Alleles in Three Ethnic Groups in Malaysia
Cytochrome P450 2C9 (CYP2C9) is the major enzyme involved in the metabolism of S-warfarin, an oral anticoagulant drug. Genetic… 
Review
2002
Review
2002
CYP2C9 polymorphisms and CYP2C9*2 genotyping primers.
The primers first suggested by Wang et al.[1] for the genotyping of the CYP2C9 Arg144Cys mutation were based on the gene… 
Review
2001
Review
2001
Identification and Functional Characterization of a New CYP 2 C 9 Variant ( CYP 2 C 9 * 51 ) Expressed among African Americans
CYP2C9 is a polymorphic gene for which there are four known allelic variants; CYP2C9*1, CYP2C9*2, CYP2C9*3, and CYP2C9*4. In the… 
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