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CYP2C8*2 Allele
Known as:
CYP2C8*2
, CYP2C8, c.805A>T
, Cytochrome P450, Family 2, Subfamily C, Polypeptide 8*2 Allele
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Human CYP2C8*2 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form of the CYP2C8 wild…
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National Institutes of Health
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Related topics
Related topics
12 relations
10q23.33
Adenosine to Thymidine Transversion Abnormality
Decreased Biochemical Activity
Iron Chelation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Cytochrome P450 2C8*2 allele in Botswana: Human genetic diversity and public health implications.
Thato Motshoge
,
Leabaneng Tawe
,
+4 authors
G. Paganotti
Acta Tropica
2016
Corpus ID: 12978545
2013
2013
CYP2C8 polymorphism frequencies among Han, Uighur, Hui, and Mongolian Chinese populations.
Xiujun Wu
,
J. Zuo
,
T. Guo
,
Li Yuan
Genetic Testing and Molecular Biomarkers
2013
Corpus ID: 30744911
PURPOSE To determine the allele frequency of three codon-changing variants (CYP2C8*2, CYP2C8*3, and CYP2C8*4) in the Han, Uighur…
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2013
2013
Prevalence of CYP2C8 polymorphisms in a North Indian population.
S. Minhas
,
N. Setia
,
S. Pandita
,
R. Saxena
,
I. Verma
,
S. Aggarwal
Genetics and Molecular Research
2013
Corpus ID: 23786826
CYP2C8 is an important member of the cytochrome P450 family of enzymes; it affects the activity of various drugs used in routine…
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2012
2012
Linkage disequilibrium between the CYP2C19*17 allele and other clinically important CYP2C allelic variants in a healthy Scandinavian population
R. Pedersen
,
M. Christensen
,
K. Brøsen
European Journal of Clinical Pharmacology
2012
Corpus ID: 1795939
In a previous study, in three Nordic populations [1], we determined the genotype and allele frequencies of the five most relevant…
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2012
2012
Distribution of human CYP2C8*2 allele in three different African populations
G. Paganotti
,
Silvia Gramolelli
,
+4 authors
R. Romano
Malaria Journal
2012
Corpus ID: 255858377
The aim of this study was to investigate cytochrome P450 2C8*2 (CYP2C8*2) distribution and allele frequency in three populations…
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2010
2010
Evaluation of the Effects of Cytochrome P450 Nonsynonymous Single-Nucleotide Polymorphisms on Tanshinol Borneol Ester Metabolism and Inhibition Potential
Duan Liu
,
Yiwen Gao
,
+10 authors
Chao Chen
Drug Metabolism And Disposition
2010
Corpus ID: 16700795
Nonsynonymous single-nucleotide polymorphisms (nsSNPs) in cytochrome P450 (P450) genes may affect drug metabolism and drug-drug…
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2007
2007
The Development of a Cocktail CYP 2 B 6 , CYP 2 C 8 , and CYP 3 A 5 Inhibition Assay and a Preliminary Assessment of Utility in a Drug Discovery Setting
C. O'donnell
,
K. Grime
,
P. Courtney
,
D. Slee
,
R. Riley
2007
Corpus ID: 1978596
Tools for studying the roles of CYP2B6, CYP2C8, and CYP3A5 in drug metabolism have recently become available. The level of…
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2006
2006
CYP2C8 polymorphism among the Portuguese
I. Cavaco
,
R. Piedade
,
J. Gil
,
V. Ribeiro
Clinical Chemistry and Laboratory Medicine
2006
Corpus ID: 1594493
Abstract Cytochrome P450 2C8 (CYP2C8) is a polymorphic phase I drug-metabolising enzyme involved in the metabolism of a wide…
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Highly Cited
2005
Highly Cited
2005
CYP2C8 polymorphism frequencies among malaria patients in Zanzibar
I. Cavaco
,
J. Strömberg-Nörklit
,
+5 authors
J. Gil
European Journal of Clinical Pharmacology
2005
Corpus ID: 35194878
Objective The determination of the prevalence of the CYP2C8 main alleles in a typical set of malaria patients in Zanzibar, as…
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2005
2005
Effect of CYP2C8 genotype on rosiglitazone pharmacokinetics
M. Hruska
,
J. Cheong
,
J. Amico
,
T. Langaee
,
R. Frye
2005
Corpus ID: 73028763
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