CYP1A1 protein, human

Known as: Cytochrome P450 Form 6, Flavoprotein-Linked Monooxygenase, CYP1A1 
Cytochrome P450 1A1 (512 aa, ~58 kDa) is encoded by the human CYP1A1 gene. This protein is involved in the metabolism of fatty acids and xenobiotics.

Topic mentions per year

Topic mentions per year

1987-2018
0204019872018

Papers overview

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Highly Cited
2001
Highly Cited
2001
We report that resveratrol (3,5,4'-trihydroxy-trans-stilbene), a phytoalexin found in grapes and other plant food, induced a… (More)
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Highly Cited
1999
Highly Cited
1999
Transcriptional activation of the human CYP1A1 gene (coding for cytochrome P450 1A1) is mediated by the aryl hydrocarbon receptor… (More)
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1999
1999
Cytochrome P450 1A1 (CYP1A1), like many monooxygenases, can produce reactive oxygen species during its catalytic cycle. Apart… (More)
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Highly Cited
1998
Highly Cited
1998
Multiple cell types contribute to the pulmonary barrier including Type I and Type II alveolar epithelium. The objective of this… (More)
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Highly Cited
1998
Highly Cited
1998
Genetically based differences in carcinogen metabolism have been related to polymorphisms of the cytochrome P450IA1 gene (CYPIA1… (More)
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Highly Cited
1998
Highly Cited
1998
Resveratrol, a compound present in a variety of plants, was recently shown to have potent chemopreventive activity against aryl… (More)
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Highly Cited
1998
Highly Cited
1998
Human cytochromes P450 1A1 (CYP1A1) and P450 1B1 (CYP1B1) catalyze the metabolic activation of a number of procarcinogens and the… (More)
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1998
1998
The gut-enriched Krüppel-like factor (GKLF) is a newly identified zinc finger-containing transcription factor. Recent studies… (More)
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1997
1997
In this report, we present a characterization of the cell-specific expression of two human cytochrome P450 genes, CYP1A1 and… (More)
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Highly Cited
1991
Highly Cited
1991
We have identified two regions in the 5'-flanking sequence of the rat quinone reductase gene that contain xenobiotic responsive… (More)
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