CYBRD1 gene

Iron deficiency and iron overload are among the most prevalent nutritional disorders worldwide. Duodenal cytochrome b (DcytB) and… Expand

Dcytb (duodenal cytochrome b) is an iron-regulated ferric reductase highly expressed in duodenal enterocytes. Its location and… Expand

Mammalian nonheme iron absorption requires reduction of dietary iron for uptake by the divalent metal ion transport system in the… Expand

Evidence is accumulating that hepcidin, a liver regulatory peptide, could be the common pathogenetic denominator of all forms of… Expand

Although the recent identification of several genes has extended our knowledge on the maintenance of body iron homeostasis, their… Expand

Background: Iron absorption increases during pregnancy to cater for the increased iron requirements of the growing fetus. Aims… Expand

Individuals with hereditary hemochromatosis suffer from systemic iron overload due to duodenal hyperabsorption. Most cases arise… Expand

Iron has a variety of functions in cellular organisms ranging from electron transport and DNA synthesis to adenosine triphosphate… Expand

Background: Although much progress has been made recently in characterising the proteins involved in duodenal iron trafficking… Expand

Dcytb has been identified as the mammalian transplasma ferric reductase that catalyzes the reduction of ferric to ferrous iron in… Expand