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CYBRD1 gene

Known as: cytochrome b561 family, member A2, ferric-chelate reductase 3, FRRS3 
 
National Institutes of Health

Papers overview

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2014
2014
A Nanoparticulate Ferritin-Core Mimetic Is Well Taken Up by HuTu 80 Duodenal Cells and Its Absorption in Mice Is Regulated by Body Iron12
BACKGROUND Iron (Fe) deficiency anemia remains the largest nutritional deficiency disorder worldwide. How the gut acquires iron… Expand
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Highly Cited
2009
Highly Cited
2009
Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency.
Iron deficiency and iron overload are among the most prevalent nutritional disorders worldwide. Duodenal cytochrome b (DcytB) and… Expand
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Highly Cited
2005
Highly Cited
2005
Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice.
Mammalian nonheme iron absorption requires reduction of dietary iron for uptake by the divalent metal ion transport system in the… Expand
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Highly Cited
2005
Highly Cited
2005
Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice.
Evidence is accumulating that hepcidin, a liver regulatory peptide, could be the common pathogenetic denominator of all forms of… Expand
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2005
2005
Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis.
Although the recent identification of several genes has extended our knowledge on the maintenance of body iron homeostasis, their… Expand
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Highly Cited
2004
Highly Cited
2004
Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat.
BACKGROUND Iron absorption increases during pregnancy to cater for the increased iron requirements of the growing fetus. AIMS… Expand
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Highly Cited
2003
Highly Cited
2003
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis
Individuals with hereditary hemochromatosis suffer from systemic iron overload due to duodenal hyperabsorption. Most cases arise… Expand
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2003
2003
Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases.
Iron has a variety of functions in cellular organisms ranging from electron transport and DNA synthesis to adenosine triphosphate… Expand
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2002
2002
Copper repletion enhances apical iron uptake and transepithelial iron transport by Caco-2 cells.
The influence of copper status on Caco-2 cell apical iron uptake and transepithelial transport was examined. Cells grown for 7-8… Expand
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2001
2001
Molecular evidence for the role of a ferric reductase in iron transport.
Duodenal cytochrome b (Dcytb) is a haem protein similar to the cytochrome b561 protein family. Dcytb is highly expressed in… Expand
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