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CYBRD1 gene

Known as: cytochrome b561 family, member A2, ferric-chelate reductase 3, FRRS3 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Duodenal Cytochrome b (DCYTB) in Iron Metabolism: An Update on Function and Regulation
Iron and ascorbate are vital cellular constituents in mammalian systems. The bulk-requirement for iron is during erythropoiesis… 
Highly Cited
2009
Highly Cited
2009
Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency.
Review
2008
Review
2008
The role of Dcytb in iron metabolism: an update.
  • A. Mckie
  • Biochemical Society transactions
  • 2008
  • Corpus ID: 33192418
Dcytb (duodenal cytochrome b) is an iron-regulated ferric reductase highly expressed in duodenal enterocytes. Its location and… 
Highly Cited
2005
Highly Cited
2005
Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice.
Mammalian nonheme iron absorption requires reduction of dietary iron for uptake by the divalent metal ion transport system in the… 
Highly Cited
2005
Highly Cited
2005
Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice.
Evidence is accumulating that hepcidin, a liver regulatory peptide, could be the common pathogenetic denominator of all forms of… 
2005
2005
Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis
Although the recent identification of several genes has extended our knowledge on the maintenance of body iron homeostasis, their… 
Highly Cited
2004
Highly Cited
2004
Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat
Background: Iron absorption increases during pregnancy to cater for the increased iron requirements of the growing fetus. Aims… 
Highly Cited
2003
Highly Cited
2003
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis
Individuals with hereditary hemochromatosis suffer from systemic iron overload due to duodenal hyperabsorption. Most cases arise… 
Highly Cited
2002
Highly Cited
2002
Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice
Background: Although much progress has been made recently in characterising the proteins involved in duodenal iron trafficking… 
Highly Cited
2002
Highly Cited
2002
Molecular and functional roles of duodenal cytochrome B (Dcytb) in iron metabolism.
Dcytb has been identified as the mammalian transplasma ferric reductase that catalyzes the reduction of ferric to ferrous iron in… 
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